Results 51 to 60 of about 875 (144)

Sendai Virus, a Strong Inducer of Anti-Lentiviral State in Ovine Cells

open access: yesVaccines, 2020
Small ruminant lentiviruses (SRLVs) are widely spread in the ovine and caprine populations, causing an incurable disease affecting animal health and production.
Lorena de Pablo-Maiso   +7 more
doaj   +1 more source

A Porcine Monoclonal Antibody Targeting a Conserved GP4 Epitope Protects against In Vivo Infection via the Induction of Broad‐Spectrum PRRSV Neutralization

open access: yesAdvanced Science, Volume 12, Issue 44, November 27, 2025.
This study developed mAb‐5F2, a monoclonal antibody targeting conserved GP4 residues (Q48/I50), which blocks the GP4‐CD163 interaction, resulting in a 78–85% reduction in viral entry. Porcineized 5F2‐pFc prevented mortality in infected piglets, reduced pulmonary viral loads, and minimized lesions. This broad‐spectrum antibody platform overcomes vaccine
Xu Chen   +12 more
wiley   +1 more source

Genetic Characterization and Phylogenetic Analysis of Small Ruminant Lentiviruses Detected in Spanish Assaf Sheep with Different Mammary Lesions

open access: yesViruses, 2018
Small Ruminant Lentiviruses (SRLVs) are widespread in many countries and cause economically relevant, slow, and persistent diseases in sheep and goats.
Elena Gayo   +5 more
doaj   +1 more source

Outer Membrane Vesicles as a Versatile Platform for Vaccine Development: Engineering Strategies, Applications and Challenges

open access: yesJournal of Extracellular Vesicles, Volume 14, Issue 9, September 2025.
ABSTRACT Outer membrane vesicles (OMVs) are nanosized vesicles naturally secreted by Gram‐negative bacteria and represent a promising platform for vaccine development. OMVs possess inherent immunostimulatory properties due to the presence of pathogen‐associated molecular patterns (PAMPs), providing self‐adjuvanting capabilities and the ability to ...
Asja Garling   +4 more
wiley   +1 more source

UEG Week 2023 Moderated Posters

open access: yes, 2023
United European Gastroenterology Journal, Volume 11, Issue S8, Page 201-534, October 2023.
wiley   +1 more source

Advances in the Study of Pluripotent Stem Cells in Livestock

open access: yesCell Proliferation, Volume 58, Issue 8, August 2025.
Livestock pluripotent stem cells include embryonic stem cells (ESCs) isolated from the inner cell mass of blastocysts and induced pluripotent stem cells (iPSCs) derived from somatic cell reprogramming. They hold significant potential for applications in livestock breed improvement, rapid propagation, human disease modelling and human organ ...
Xinyi Zhou   +6 more
wiley   +1 more source

Investigation of small ruminant lentivirus infections by serological and molecular methods in eastern mediterranean region [PDF]

open access: yesEurasian Journal of Veterinary Sciences
Aim: The aim of this study was to investigate the presence of small ruminant lentivirus infections in samples taken from goat and sheep farms. Materials and Methods: In this study, leukocyte and blood serum samples were taken from a total of 700 animals,
Fırat Doğan   +3 more
doaj  

Investigation, management and control of a maedi outbreak in Norway in 2019-2020

open access: yesActa Veterinaria Scandinavica
Background Visna-maedi is a notifiable disease in Norway, and eliminating the disease is a national goal. The import of sheep into Norway is very limited, and strict regulations apply to the movement of small ruminants between flocks and within defined ...
Grim Rømo   +11 more
doaj   +1 more source

Immune response dynamics of recent and chronic small ruminant lentivirus infection in the male reproductive system

open access: yesSemina: Ciências Agrárias, 2023
The objective of this study was to analyze the immune responses of bucks to small ruminant lentivirus (SRLV) with a focus on the reproductive system of males with recent and chronic infection.
Renato Mesquita Peixoto   +7 more
doaj   +1 more source

Maternal transmission of Small Ruminant Lentivirus has no epidemiological importance

open access: yesPreventive Veterinary Medicine
The relative importance of maternal and horizontal transmission of small ruminant lentivirus (SRLV), the causative organism in maedi-visna, is poorly understood. Review of the literature shows that maternal transmission is inefficient, infecting only about 10-25 % of the lambs of infected ewes.
Illius, Andrew W., Savill, Nicholas J.
openaire   +2 more sources

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