Results 1 to 10 of about 539 (147)

Immunogenicity, security and protection against small ruminant lentivirus (SRLV) challenge in sheep, induced by intranasal immunization with a recombinant Sendai virus vector expressing SRLV gag-P25 [PDF]

Veterinary Quarterly
Small ruminant lentiviruses (SRLV) are responsible for significant economic losses in sheep and goat farming; however, effective vaccination strategies remain unavailable.
Álex Gómez, Idoia Glaria, Irati Moncayola, Irache Echeverría, Ana Rodríguez-Largo, Ignacio de Blas, Estela Pérez, Marta Pérez, Sergio Villanueva-Saz, Benhur Lee, Alicia de Diego, Ricardo de Miguel, Lluís Luján, Ramsés Reina   +13 more
exaly   +9 more sources

Permissiveness of different TMEM154 genotype cell lines to different SRLV genotypes/subtypes [PDF]

Journal of Virology
Small ruminant lentiviruses (SRLVs) are a heterogeneous group of viruses that infect goats and sheep worldwide, for which no cures or effective vaccines are available.
Daniele Avanzato, Margherita Profiti, Sérgio Rosati   +2 more
exaly   +8 more sources

Genomic Epidemiology and Heterogeneity of SRLV in Italy from 1998 to 2019 [PDF]

Viruses, 2021
Small ruminant lentiviruses (SRLV) are viruses that retro-transcribe RNA to DNA and show high rates of genetic variability. SRLV affect animals with strains specific for each host species (sheep or goats), resulting in a series of clinical manifestations
Moira Bazzucchi, Ilaria Pierini, Paola Gobbi   +2 more
exaly   +5 more sources

First Report of SNPs Detection in TMEM154 Gene in Sheep from Poland and Their Association with SRLV Infection Status [PDF]

Pathogens
Small ruminant lentiviruses (SRLVs) infect sheep, causing a multiorganic disease called maedi-visna or ovine progressive pneumonia, which significantly affects the production and welfare of sheep, generating serious economic losses.
Magdalena Materniak-Kornas, Katarzyna Piórkowska, Katarzyna Ropka-Molik, Adrianna Dominika Musiał, Joanna Kowalik, Anna Kycko, Jacek Kuźmak   +6 more
doaj   +4 more sources

miRNA expression patterns in blood leukocytes and milk somatic cells of goats infected with small ruminant lentivirus (SRLV)

Scientific Reports, 2022
The study aims to determine the selected miRNAs expression in milk somatic cells (MSC) and blood leukocytes (BL) of SRLV-seronegative (SRLV-SN) and SRLV-seropositive (SRLV-SP) goats.
Justyna Jarczak, Michał Czopowicz, Jarosław Kaba   +2 more
exaly   +2 more sources

Preliminary study on paratuberculosis, small ruminant lentivirus, and co-infection in Emilia Romagna flocks [PDF]

Open Veterinary Journal
Background: Small ruminant lentiviruses (SRLVs) and Mycobacterium avium subsp. paratuberculosis (MAP) are major pathogens affecting sheep and goats, leading to significant economic losses and animal welfare concerns. Aim: To investigate the frequency
Elisabetta Mondo, Raffaele Scarpellini, Erika Esposito, Mariana Roccaro, Lara Pusinich, Simone PierMatteo, Silvia Piva   +6 more
doaj   +2 more sources

Investigation of an association between in vitro expression of TMEM154 and PARP14 genes and restriction of SRLV infection in primary skin cells of Carpathian goats [PDF]

Journal of Veterinary Research
Small ruminant lentivirus (SRLV) infections occur worldwide in goats and sheep and have negative impact on the production and welfare of animals.
Materniak-Kornas Magdalena, Smagacz Marlena, Ropka-Molik Katarzyna, Kawęcka Aldona, Sikora Jacek, Michał Kuźmak Jacek   +5 more
doaj   +2 more sources

A Look Under the Carpet of a Successful Eradication Campaign Against Small Ruminant Lentiviruses [PDF]

Pathogens
Small ruminant lentiviruses (SRLVs) are widespread and have a long co-evolutionary history with their hosts, namely sheep and goats. These viruses induce insidious pathologies, causing significant financial losses and animal welfare issues for the ...
Fadri Vincenz, Maksym Samoilenko, Carlos Eduardo Abril, Patrik Zanolari, Giuseppe Bertoni, Beat Thomann   +5 more
doaj   +2 more sources

Characterization of a recombinant Sendai virus vector encoding the small ruminant lentivirus gag-P25: antiviral properties in vitro and transgene expression in sheep [PDF]

Veterinary Research
Small ruminant lentiviruses (SRLV) cause multisystemic chronic inflammatory disease and significant economic losses in sheep and goats worldwide. However, no vaccines or therapies are currently available.
Álex Gómez, Idoia Glaria, Irati Moncayola, Irache Echeverría, Javier Arrizabalaga, Ana Rodríguez-Largo, Ignacio de Blas, Delia Lacasta, Estela Pérez, Marta Pérez, Alicia De Diego, Ricardo De-Miguel, Benhur Lee, Lluís Luján, Ramsés Reina   +14 more
doaj   +2 more sources

The genetic variability of small-ruminant lentiviruses and its impact on tropism, the development of diagnostic tests and vaccines and the effectiveness of control programmes [PDF]

Journal of Veterinary Research, 2023
Maedi-visna virus and caprine arthritis encephalitis virus are two closely related lentiviruses which cause multisystemic, progressive and persistent infection in goats and sheep.
Olech Monika
doaj   +2 more sources