Results 121 to 130 of about 15,601,125 (299)

Application of Variational Autoencoder‐Based Clustering for Geophysical Fluid Circulations With Small Sample Size

Journal of Geophysical Research: Machine Learning and Computation
The variational autoencoder (VAE), a deep generative model, can extract a good feature representation for clustering from complex data; however, the use of this algorithm in the geophysical fluid circulation has been limited.
Kunihiro Aoki, Hideyuki Nakano, Nariaki Hirose, Norihisa Usui, Kei Sakamoto, Takahiro Toyoda, Shogo Urakawa, Yuma Kawakami   +7 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Human Resource Management With Small Firms; Facts And Explanations [PDF]

This study examines determinants of the formalization of HRM practices with small firms. We derive five hypotheses that identify possible determinants of the level of formalization, including firm size, family business, the availability of an HRM ...
Uhlaner, L.M., Kok, J.M.P. de, Thurik, A.R.   +2 more
core  

Rank correlation inferences for clustered data with small sample size. [PDF]

Stat Neerl, 2022
Hunsberger S, Long L, Reese SE, Hong GH, Myles IA, Zerbe CS, Chetchotisakd P, Shih JH.   +7 more
europepmc   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Small RNA size distribution.

, 2015
The size of small RNA from each sample was plotted versus frequency (0.0–1.0) among distinct sequences (A) or total sequences (B) to eliminate the bias of different sequencing depth.
Ning Zhang (23771), Zhanyuan J. Zhang (135296), Sha Lu (753027), Kristin Bilyeu (551052), Xiaoyan Yin (560599), James Schoelz (753028), William Spollen (692141), Dong Xu (21616)   +7 more
core   +1 more source

Quantifying Podocyte Number in a Small Sample Size of Glomeruli with CUBIC to Evaluate Podocyte Depletion of db/db Mice. [PDF]

J Diabetes Res, 2023
Shi J, Hu Y, Shao G, Zhu Y, Zhao Z, Xu Y, Zhang Z, Wu H.   +7 more
europepmc   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Performance Evaluation of Publicly Funded Agricultural Research Projects with Light-TabNet

Applied Sciences
This study focuses on the performance evaluation of publicly funded agricultural research projects in a structured tabular-data setting characterized by small sample size and heterogeneous features.
Zelin Liu, Lu Fan, Qiulian Chen, Haipeng Li, Ailan Wei   +4 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source