Results 91 to 100 of about 590,638 (263)

Predicting the stability of profiling signals of small RNAs

Profiling is a process that finds similarities between different RNA secondary structures by extracting signals from the Boltzmann sampling. The reproducibility of profiling can be identified by the standard deviation of number of features among Boltzmann samples. We found a strong relationship between the frequency of each helix class and its standard
Li, Qiuyun, Riehl, Manda
openaire   +2 more sources

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Small-Signal Stability Analysis of Power Systems by Implicit Multilinear Models

IEEE Access
This paper proposes a new approach to perform small-signal stability analysis based on linearization of implicit multilinear models. Multilinear models describe the system dynamics by multilinear functions of state, input, and algebraic variables.
Christoph Kaufmann, Georg Pangalos, Gerwald Lichtenberg, Oriol Gomis-Bellmunt   +3 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Dynamic impact of hybrid wind-solar photovoltaic power injection on small signal stability of Nigerian 11kV power system using Self Organizing Map neural network

Scientific African
Power industry reorganization, legislation on greenhouse gas emissions and inadequate conventional generation capacity encourage the idea of incorporating Distributed Generation (DG) into the distribution networks as unconventional sources of power ...
ADEBIMPE Abiodun Michael, OLULOPE Paul Kehinde, OLAJIGA Benson Olawale, OLAJUYIN Elijah Adebayo, ADEOYE Oluwatosin Samuel   +4 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

A New Fuzzy Stabilizer Based on Online Learning Algorithm for Damping of Low-Frequency Oscillations [PDF]

Journal of Optimization in Industrial Engineering, 2015
A multi objective Honey Bee Mating Optimization (HBMO) designed by online learning mechanism is proposed in this paper to optimize the double Fuzzy-Lead-Lag (FLL) stabilizer parameters in order to improve low-frequency oscillations in a multi machine ...
Ali Ghasemi, Mohammad Javad Golkar, Mohammad Eslami   +2 more
doaj  

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source