Results 21 to 30 of about 10,367,950 (284)
Small‐Molecule Modulators for Epigenetics Targets
ChemMedChem, 2013 A capital conference: Influencing epigenetic mechanisms may be highly relevant for future therapies of various diseases such as cancer, inflammation, and metabolic disorders. Leading experts in the field gathered in Berlin on June 5-6, 2013 at a Bayer HealthCare Life Science Workshop to share recent success stories and to discuss future trends.
Knapp, S, Weinmann, H
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Advances of small molecule targeting of kinases [PDF]
Current Opinion in Chemical Biology, 2017 Reversible protein phosphorylation regulates virtually all aspects of life in the cell. As a result, dysregulation of protein kinases, the enzymes responsible for transferring phosphate groups from ATP to proteins, are often the cause or consequence of many human diseases including cancer.
Norbert, Berndt +2 more
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An Enhanced Feature Extraction Framework for Cross-Modal Image–Text Retrieval
Remote SensingIn general, remote sensing images depict intricate scenes. In cross-modal retrieval tasks involving remote sensing images, the accompanying text includes numerus information with an emphasis on mainly large objects due to higher attention, and the ...
Jinzhi Zhang +4 more
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, 2014 A proverbial objective in nanomaterial science is to construct low-dimensional nanoparticle (NP) assemblies with fascinating properties, which have shown great promise in optical, electronic and biomedical applications.
Yue, Hua +10 more
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Targeting Large and Small [PDF]
Optik & Photonik, 2009 AbstractA corporation that grows dynamically through acquisition needs two good strategies for success: one for the growth itself and one for the integration of the acquired companies. The positive development of the fiber optics business unit within the Leoni group suggests that the management has set the right course for the future.
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Multimodal feedback for the acquisition of small targets [PDF]
Ergonomics, 2005 This paper examines how multimodal feedback assists small-target acquisition in graphical user interfaces. All combinations of three feedback modes are analysed: non-speech audio; tactile; and pseudo-haptic "sticky" feedback. The tactile conditions used stimulation through vibration (rather than force-feedback), and the sticky conditions were ...
Andy, Cockburn, Stephen, Brewster
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Small molecule inhibitors targeting the cancers
MedComm, 2022 AbstractCompared with traditional therapies, targeted therapy has merits in selectivity, efficacy, and tolerability. Small molecule inhibitors are one of the primary targeted therapies for cancer. Due to their advantages in a wide range of targets, convenient medication, and the ability to penetrate into the central nervous system, many efforts have ...
Gui‐Hong Liu +4 more
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Frontiers in Plant ScienceThe aim of this study is to propose a lightweight YOLOv8n maize seedling detection algorithm that incorporates multi-scale features to address the problems of large number of model parameters and computation, low real-time performance, and small ...
Pengbo Feng +4 more
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Applied SciencesImage detection technology is of paramount importance across various fields. This significance is not only seen in general images with everyday scenes but also holds substantial research value in the field of remote sensing. Remote sensing images involve
Qiang Fu +3 more
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Targeting Protein Stability with a Small Molecule [PDF]
Cell, 2006 Both genetic approaches and small-molecule inhibitors can be used to perturb protein function. Banaszynski et al. (2006) now describe a strategy to regulate the stability of a target protein, in which specificity is provided by a genetically encoded tag and temporal control is imparted by a small molecule.
Lampson, Michael A., Kapoor, Tarun M.
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