Results 171 to 180 of about 37,476 (270)

Small ubiquitin-related modifier is secreted and shows cytokine-like activity.

open access: yesBiological and Pharmaceutical Bulletin, 2008
Hidetaka Hosono, H. Yokosawa
semanticscholar   +1 more source

Ubiquitination in cancer: mechanisms and therapeutic opportunities. [PDF]

open access: yesCancer Commun (Lond)
Zhu S   +7 more
europepmc   +1 more source

Isoform-specific monobody inhibitors of small ubiquitin-related modifiers engineered using structure-guided library design

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2011
R. Gilbreth   +8 more
semanticscholar   +1 more source

A Rare RIPK3 Variant Enhances Necroptosis and Promotes Inflammation in a Still's Disease‐like Autoinflammatory Syndrome

open access: yesArthritis &Rheumatology, Accepted Article.
Objectives Still's Disease represents a prototypical polygenic systemic autoinflammatory diseases (SAIDs), characterized by recurrent systemic inflammation and dysregulation of innate immunity. Despite extensive clinical characterization, familial clustering Still's disease remains unreported.
Longfang Chen   +23 more
wiley   +1 more source

Identifying systemic lupus erythematosus from serum proteomic profiles using machine learning and genetic risk stratification

open access: yesArthritis &Rheumatology, Accepted Article.
Objectives Proteome‐wide risk models for lupus remain underexplored. We developed classification models to identify lupus from serum proteomic profiles. Methods Lupus patients and individuals with other autoimmune diseases in the UK Biobank were included.
Mehmet Hocaoǧlu   +2 more
wiley   +1 more source

Identification of biomarkers associated with SUMO modification in heart failure. [PDF]

open access: yesMedicine (Baltimore)
Chen Z   +5 more
europepmc   +1 more source

The 3‐Hit Metabolic Signaling Model for Autism Spectrum Disorder: A Summary

open access: yesAutism Research, EarlyView.
ABSTRACT Autism spectrum disorder (ASD) is a highly heritable yet environmentally sensitive neurodevelopmental condition whose biological heterogeneity has resisted a unifying causal explanation for over 100 years. The 3‐hit metabolic signaling model proposes that ASD arises from abnormal persistence of an evolutionarily conserved stress‐response ...
Robert K. Naviaux
wiley   +1 more source

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