Results 21 to 30 of about 81,577 (264)

Protein-Based Nanomaterials for Cancer Therapy: A Comparative and Translational Perspective

Pharmaceutics
Over the past decade, the use of nanomaterials and nanomedical devices has been increasingly explored for cancer treatment. Although the outcomes of conventional therapies have improved patient survival, these approaches still present important ...
Juan Gonzalez-Valdivieso, Javier Gutiérrez, Jonathan Alexander Vásquez Calero, Sara Escalera-Anzola, Raquel Muñoz, Francisco Javier Arias, M. Ángeles Rojo, Alessandra Girotti   +7 more
doaj   +1 more source

Anomaly diagnosis of photovoltaic power generation system through fusing time series data with its same-source images

Energy Reports
With the increasing use of photovoltaic (PV) systems in the global energy transition, accurate anomaly diagnosis is critical for ensuring stable and efficient operation.
Wenke Ma, Changgeng Zhou, Yifan Lu, Yisheng Lv, Chengdong Li   +4 more
doaj   +1 more source

Safe evacuation framework with intelligent dynamic exit sign system and demonstration in tunnel fire

Journal of Safety Science and Resilience
Emergency exit sign systems guide occupants to safety, but they may fail in fires when smoke blocks routes. This study introduces an Intelligent Dynamic Exit Sign (IDES) system, integrating a fire-detection sensor network with dynamic sign patterns ...
Ho Yin Wong, Meng Wang, Xiaoning Zhang, Yuxin Zhang, Ming Chi Wong, Xinyan Huang   +5 more
doaj   +1 more source

Inhibited Channel Potential of 3D NAND Flash Memory String According to Transient Time

Applied Sciences, 2023
The channel potential of natural local self-boosting (NLSB) effects in 16-layer 3D NAND flash memory was analyzed according to transient time. After a program pulse was applied to the selected word line (WL) of the inhibited string channel, the channel ...
Taeyoung Cho, Hyunju Kim, Myounggon Kang
doaj   +1 more source

Towards energy efficiency: retrofitting existing office buildings using smart technologies

Journal of Engineering and Applied Science, 2023
Buildings are considered one of the main causes of increasing CO2 emissions due to their excessive consumption of energy. The drive towards sustainability represents a challenge especially in existing buildings.
Mona Azouz, Sarah Elariane
doaj   +1 more source

Estimating the Smart Readiness Indicator in the Italian Residential Building Stock in Different Scenarios

Energies, 2021
The Energy Performance of Buildings Directive 2018/844/EU introduced the smart readiness indicator (SRI) to provide a framework to evaluate and promote building smartness in Europe. In order to establish a methodological framework for the SRI calculation,
Laura Canale, Marianna De Monaco, Biagio Di Pietra, Giovanni Puglisi, Giorgio Ficco, Ilaria Bertini, Marco Dell’Isola   +6 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Structural Design Optimization of Flat Slab Hospital Buildings Using Genetic Algorithms

Buildings, 2022
The construction costs of hospital buildings are relatively high due to the need to fulfill their complex functions and avoid mishaps. In this context, this study aims to minimize the total construction costs of hospitals while still satisfying the ...
Ahmed Aidy, Mohammed Rady, Ibrahim Mohsen Mashhour, Sameh Youssef Mahfouz   +3 more
doaj   +1 more source

On Smart-Buildings and their Integration into the Smart-Grid

, 2020
Today's electrical grid is undergoing deep changes, resulting from the large integration of distributed Renewable Energy Sources (RES) in an effort to decarbonize the generation of electrical energy. In addition to the emergence of this volatile electricity production, the worldwide demand for electricity increases due to a growing population and the ...
openaire   +2 more sources

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source