Results 51 to 60 of about 288,931 (256)

Kaempferia parviflora Extract Stabilizes Cartilage Homeostasis via TIMP-1–Associated Matrix Modulation in Monosodium Iodoacetate–Induced Rat Osteoarthritis

open access: yesPharmaceuticals
Background: Osteoarthritis (OA) is a degenerative joint disease characterized by extracellular matrix (ECM) breakdown, inflammation, and pain-associated functional impairment.
DongHoon Lee   +7 more
doaj   +1 more source

The accuracy of severity assessment tools designed for community acquired pneumonia among elderly patients with hospital acquired pneumonia

open access: yesAsian Journal of Medical Sciences, 2016
Background: Pneumonia severity assessment is an essential initial step in the evaluation of patients with community acquired pneumonia. Many validated severity assessment tools were designed for use in this setting.
Doha Rasheedy
doaj   +1 more source

New drugs in cancer chemotherapy [PDF]

open access: yes, 2010
Tumorske stanice su osjetljivije od normalnih stanica na kemoterapijske lijekove. Cilj lijekova koji se koriste u kemoterapiji tumora je izazivanje apoptoze tumorskih stanica. U ovom radu izložen je pregled antitumorskih lijekova.
Hanžić, Nikolina
core   +2 more sources

Communication Architecture for Tracking and Interoperable Services at Hospitals: A Real Deployment Experience [PDF]

open access: yes, 2011
Any new hospital communication architecture has to support existing services, but at the same time new added features should not affect normal tasks. This article deals with issues regarding old and new systems’ interoperability, as well as the effect ...
Alcarria Garrido, Ramón Pablo   +3 more
core   +2 more sources

Remote Monitoring in Myasthenia Gravis: Exploring Symptom Variability

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare, autoimmune disorder characterized by fluctuating muscle weakness and potential life‐threatening crises. While continuous specialized care is essential, access barriers often delay timely interventions. To address this, we developed MyaLink, a telemedical platform for MG patients.
Maike Stein   +13 more
wiley   +1 more source

Enzyme-Responsive Materials as Carriers for Improving Photodynamic Therapy

open access: yesFrontiers in Chemistry, 2021
Photodynamic therapy (PDT) is a mini-invasive therapy on malignancies via reactive oxygen species (ROS) induced by photosenitizer (PS) upon light irradiation. However, poor target of PS to tumor limits the clinical application of PDT.
Houhe Liu   +7 more
doaj   +1 more source

Onasemnogene Abeparvovec in Type I Spinal Muscular Atrophy: 24‐Month Follow‐Up From the Italian Registry

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane   +43 more
wiley   +1 more source

Development and validation of a risk score for chronic kidney disease in HIV infection using prospective cohort data from the D:A:D study. [PDF]

open access: yes, 2015
Chronic kidney disease (CKD) is a major health issue for HIV-positive individuals, associated with increased morbidity and mortality. Development and implementation of a risk score model for CKD would allow comparison of the risks and benefits of adding ...
D:A:D study group, .   +18 more
core  

Following the donor-designed path to Mozambique’s US$2.2 billion secret debt deal [PDF]

open access: yes, 2016
Strenuous efforts by donors and lenders over four decades turned Mozambique from a socialist success story into a neoliberal capitalist one. The private sector dominates; a domestic elite dependent on foreign companies has been created. But a secret US$2
Hanlon, Joseph
core   +2 more sources

Evaluation of a novel EHR sidecar application to display RA clinical outcomes during clinic visits: results of a stepped‐wedge cluster randomized pragmatic trial

open access: yesArthritis Care &Research, Accepted Article.
Objective We developed a novel EHR sidecar application to visualize key rheumatoid arthritis (RA) outcomes, including disease activity, physical function, and pain, via a patient‐facing graphical interface designed for use during outpatient visits (“RA PRO dashboard”).
Gabriela Schmajuk   +16 more
wiley   +1 more source

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