Results 51 to 60 of about 407,922 (287)
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
A ROS2 based communication architecture for control in collaborative and intelligent automation systems [PDF]
, 2019 Collaborative robots are becoming part of intelligent automation systems in modern industry. Development and control of such systems differs from traditional automation methods and consequently leads to new challenges. Thankfully, Robot Operating System (
Bengtsson, Kristofer +4 more
core +3 more sources
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Frontiers in Energy Research, 2022 Experimental investigations have been conducted to improve the cooling effectiveness of film-cooling technology. A multiple row of cylindrical holes at the flat surface was considered by inclining the holes at 35° along the streamwise direction.
Jaemun Choi +5 more
doaj +1 more source
Identifying smart design attributes for Industry 4.0 customization using a clustering Genetic Algorithm [PDF]
, 2016 Industry 4.0 aims at achieving mass customization at a mass production cost. A key component to realizing this is accurate prediction of customer needs and wants, which is however a challenging issue due to the lack of smart analytics tools.
Chen, Yi +4 more
core +1 more source
FEBS Open Bio, EarlyView.A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
Study on UV Energy Effects in High Aspect Ratio Patterning via the Self-propagating Photopolymer Waveguide (SPPW) Method [PDF]
한국정밀공학회지This study quantitatively examines the impact of ultraviolet (UV) intensity and energy on the formation of high aspect ratio (HAR) microstructures using the Self-Propagating Photopolymer Waveguide (SPPW) process.
Jun Ho Song +4 more
doaj +1 more source
Product Service System Innovation in the Smart City [PDF]
, 2018 Product service systems (PSS) may usefully form part of the mix of innovations necessary to move society toward more sustainable futures. However, despite such potential, PSS implementation is highly uneven and limited.
Aoun C +14 more
core +1 more source
Harnessing Fungal Biowelding for Constructing Mycelium‐Engineered Materials
Advanced Engineering Materials, EarlyView.Mycelium‐bound composites (MBCs) offer low‐carbon alternatives for construction, yet interfacial bonding remains a critical challenge. This review examines fungal biowelding as a biocompatible adhesive, elucidating mycelium‐mediated interfacial mechanisms and their role in material assembly. Strategies to optimize biowelding are discussed, highlighting
Xue Brenda Bai +2 more
wiley +1 more source
International Journal of Food PropertiesRed pepper (Capsicum annuum L.) is an important crop in South Korea. The metabolite composition of plants is influenced by environmental factors such as soil and climate. However, the geographical effects remain unclear.
Gi-Un Seong +7 more
doaj +1 more source