Results 61 to 70 of about 4,641,193 (302)

A digital life-cycle management framework for sustainable smart manufacturing in energy intensive industries

open access: yesJournal of Cleaner Production, 2023
Energy intensive industries can be classified into those that process metal, glass, ceramics, paper, cement, and bulk chemicals. They are associated with significantly high proportions of carbon emissions, consume a lot of energy and raw materials, and ...
Malarvizhi Kaniappan Chinnathai   +1 more
semanticscholar   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Effect of Direct Recycling Hot Press Forging Parameters on Mechanical Properties and Surface Integrity of AA7075 Aluminum Alloys

open access: yesMetals, 2022
The current practice in aluminum recycling plants is to change the waste into molten metal through the conventional recycling (CR) manufacturing process.
Nasha Emieza Ruhaizat   +6 more
doaj   +1 more source

Evaluating the transparency capability of smart manufacturing systems [PDF]

open access: yes
Transparency encompasses the potential to monitor operations instantaneously so that required corrective actions can be taken as needed. Transparency entails the ability to track processes in real-time, enhance the visibility of the operations, and ...
Garza-Reyes, J.   +3 more
core   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

A Numerical Study on the Effects of Inlet Velocity Variation on Gas-particle Flow in a Cyclone Separator [PDF]

open access: yes한국정밀공학회지
This study investigated the influence of inlet velocity on the internal flow characteristics and particle separation performance of a cyclone separator.
Geonho Kim   +3 more
doaj   +1 more source

A wearable fetal movement detection system for pregnant women

open access: yesFrontiers in Medicine, 2023
A wearable device-based fetal movement detection system for pregnant women is proposed to resolve the problems of low accuracy of fetal movement detection by fetal heart monitor, difficulties of fetal movement monitoring by pregnant women in person, and ...
Manping Qin   +4 more
doaj   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Optimizing Cloud-Edge Integration for Task Scheduling in Smart Manufacturing Lines: A Multi-objective Method

open access: yesAnbar Journal of Engineering Sciences
This study introduces a cloud-edge smart manufacturing architecture for task scheduling using a hybrid NSGA-II and Improved Monarch Butterfly Optimization approach.
Ahmed Ahmed   +3 more
doaj   +1 more source

A framework to design smart manufacturing systems for Industry 5.0 based on the human-automation symbiosis

open access: yesInternational journal of computer integrated manufacturing (Print), 2023
The concept of Industry 5.0 (I5.0) promotes the human-centricity as the core value behind the evolution of smart manufacturing systems (SMSs), based on a novel use of digital technologies in the design and management of modern industrial systems to take ...
M. Peruzzini, E. Prati, M. Pellicciari
semanticscholar   +1 more source

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