Results 51 to 60 of about 965,341 (296)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Morphology simulation of drop-on-demand inkjet-printed droplets

npj Flexible Electronics, 2022
Inkjet-printed electronics have become a popular research topic in recent years. For common drop-on-demand (DOD) inkjet printing technology, uneven edges are a universal problem.
Shaowei Hu, Wenbo Zhu, Wanchun Yang, Mingyu Li   +3 more
doaj   +1 more source

Metformin Hydrochloride Significantly Inhibits Rotavirus Infection in Caco2 Cell Line, Intestinal Organoids, and Mice

Pharmaceuticals, 2023
Rotavirus is one of the main pathogens that causes severe diarrhea in children under the age of 5, primarily infecting the enterocytes of the small intestine.
Rui Zhang, Cui Feng, Dandan Luo, Ruibo Zhao, Perumal Ramesh Kannan, Yuebang Yin, Muhammad Zubair Iqbal, Yeting Hu, Xiangdong Kong   +8 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Snap evaporation of droplets on smooth topographies

Nature Communications, 2018
Droplet evaporation control has applications in inkjet printing and surface patterning. Here, the authors show that on slippery curved substrates droplets evaporate by slowly retracting and then suddenly snapping, which can be exploited to design ...
Gary G. Wells, Élfego Ruiz-Gutiérrez, Youen Le Lirzin, Anthony Nourry, Bethany V. Orme, Marc Pradas, Rodrigo Ledesma-Aguilar   +6 more
doaj   +1 more source

Polymeric Hydrogels—A Promising Platform in Enhancing Water Security for a Sustainable Future

Advanced Materials Interfaces, 2021
Although water is essential for global health and the socio‐economic development of modern society, providing fresh water universally in a sustainable and affordable manner, for both developing and industrialized communities, is challenging.
Siew‐Leng Loo, Lía Vásquez, Athanassia Athanassiou, Despina Fragouli   +3 more
doaj   +1 more source

Droplet-Based Microfluidic Preparation of Shape-Variable Alginate Hydrogel Magnetic Micromotors

Nanomaterials, 2021
This article introduces a facile droplet-based microfluidic method for the preparation of Fe3O4-incorporated alginate hydrogel magnetic micromotors with variable shapes.
Cheng Zhang, Yong Wang, Yuduo Chen, Xing Ma, Wenjun Chen   +4 more
doaj   +1 more source

Regenerated Cellulose Fiber Solar Cell

, 2017
Wearable electronics and smart textiles are growing fields in the cause to integrate modern communication and computing tools into clothing instead of carrying around smart phones and tablets.
Chien, Huei-Ting, Ebner, Michael, Friedel, Bettina, Mayrhofer, Claudia, Schennach, Robert, Zankel, Armin   +5 more
core   +1 more source

Ferroelectrics as smart mechanical materials [PDF]

, 2017
This is the peer reviewed version of the following article: Cordero, K., Domingo Marimon, Neus, Abdollahi, A., Sort Viñas, Jordi, Catalan, G. Ferroelectrics as smart mechanical materials. "Advanced materials", 21 Juliol 2017, vol. 29, núm. 37, p.
Abdollahi Hosnijeh, Amir, Catalan, Gustau, Cordero Edwards, Kumara, Domingo Marimon, Neus, Sort Viñas, Jordi   +4 more
core   +3 more sources

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source