Results 11 to 20 of about 36,611 (290)

Intravital Microscopy Reveals Endothelial Transcytosis Contributing to Significant Tumor Accumulation of Albumin Nanoparticles

Pharmaceutics, 2023
The principle of enhanced permeability and retention (EPR) effect has been used to design anti-cancer nanomedicines over decades. However, it is being challenged due to the poor clinical outcome of nanoparticles and controversial physiological foundation.
Guoguang Wei, Sihang Zhang, Sheng Yu, Wei Lu   +3 more
doaj   +1 more source

Medical Uses of Synthetic Piezoelectric Polymers; 2020-2021 Overview

Journal of Innovative Science and Engineering, 2022
Smart materials that can reverse one or more of their functional or structural properties according to the external stimulus are the most trending topic of our time.
Hilal Yilmaz
doaj   +1 more source

Smart Polymer Surfaces

Macromolecules, 2003
A methodology is demonstrated for creating responsive polymer surfaces that can alter their wetting characteristics when exposed to a humid environment. For this, we take advantage of the surface partitioning of block copolymers at the polymer/air interface and utilize a hydrophilic group at the end of the surface-active block.
Anastasiadis, S.H., Retsos, H., Pispas, S., Hadjichristidis, N., Neophytides, S.   +4 more
openaire   +2 more sources

Small interfering RNA delivery to the neurons near the amyloid plaques for improved treatment of Alzheimer׳s disease

Acta Pharmaceutica Sinica B, 2019
Gene therapy represents a promising treatment for the Alzheimer׳s disease (AD). However, gene delivery specific to brain lesions through systemic administration remains big challenge.
Qian Guo, Xiaoyao Zheng, Peng Yang, Xiaoying Pang, Kang Qian, Pengzhen Wang, Shuting Xu, Dongyu Sheng, Liuchang Wang, Jinxu Cao, Wei Lu, Qizhi Zhang, Xinguo Jiang   +12 more
doaj   +1 more source

Smart Polymeric Nanoparticles in Cancer Immunotherapy

Pharmaceutics, 2023
Cancer develops with unexpected mutations and causes death in many patients. Among the different cancer treatment strategies, immunotherapy is promising with the benefits of high specificity and accuracy, as well as modulating immune responses ...
Zhecheng Yu, Xingyue Shen, Han Yu, Haohong Tu, Chuda Chittasupho, Yunqi Zhao   +5 more
doaj   +1 more source

A new approach to thermal responsivity and hydrodynamics of poly(N-isopropylacrylamide) in aqueous solution: all-atom and mesoscopic simulations

Materials Research Express, 2021
In this study, the impact of chemical and physical characteristics of poly(N-isopropylacrylamide) (PNIPAm) in water on its thermoresponsive behavior and aggregation was investigated via all-atom and mesoscopic simulations.
Sajad Rasouli, Mohammad Reza Moghbeli, Seyed Majid Hashemianzadeh   +2 more
doaj   +1 more source

Cellulose nanocrystals in smart and stimuli-responsive materials: a review

Materials Today Advances, 2020
“Smart” stimuli-responsive materials have been the subject of decades of research because of their versatility and particularly their use in medical and sensing applications.
R. Nasseri, C.P. Deutschman, L. Han, M.A. Pope, K.C. Tam   +4 more
doaj   +1 more source

Design of acrylamide-based thermoresponsive copolymer with potential capability for physical network formation in water: a molecular dynamics study

Materials Research Express, 2022
In this work, a new smart copolymer of poly(N-isopropylacrylamide)- b -polyacrylamide- b -poly(N-isopropylacrylamide) (PNIPAm- b -PAM- b -PNIPAm) was designed as an efficient thermo-sensitive polymer with a potential for formation a physical network ...
Sajad Rasouli, Mohammad Reza Moghbeli, Seyed Majid Hashemianzadeh   +2 more
doaj   +1 more source

Insight in thermomechanical constitutive modeling of shape memory polymers

Frontiers in Mechanical Engineering, 2022
Shape memory polymers (SMPs) are a new member of the smart materials family. SMPs have found wide applications or potential applications in almost all manmade structures and devices.
Amir Shojaei, Wei Xu, Cheng Yan, Qianxi Yang, Guoqiang Li   +4 more
doaj   +1 more source

Oral delivery of exenatide-loaded hybrid zein nanoparticles for stable blood glucose control and β-cell repair of type 2 diabetes mice

Journal of Nanobiotechnology, 2020
Background Exenatide is an insulinotropic peptide drug for type 2 diabetes treatment with low risk of hypoglycemia, and is administrated by subcutaneous injection.
Xiaoyan Bao, Kang Qian, Ping Yao
doaj   +1 more source