Results 41 to 50 of about 10,270 (304)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Real-Time Testing Optimal Power Flow in Smart-Transformer-Based Meshed Hybrid Microgrids: Design and Validation

Energies
The smart transformer (ST) is a multiport and multi-stage converter that allows for the formation of meshed hybrid microgrids (MHMs) by enabling AC-DC ports in medium and low voltage.
Rafael A. Núñez-Rodríguez, Clodomiro Unsihuay-Vila, Johnny Posada, Omar Pinzón-Ardila, Alexandre Rasi Aoki, Rodrigo Bueno-Otto   +5 more
doaj   +1 more source

Smart Distribution Transformer for Smart Grid [PDF]

, 2016
In this thesis, a smart distribution transformer which improves power quality in the electrical power distribution grid is discussed. The proposed system is comprised of an existing line frequency (LF) distribution transformer connected to a power ...
Kang, Taeyong
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Smart Transformer-Assisted Frequency Control Mechanism for RES Penetrated Power Systems Considering Metaheuristic-Based Secondary Controller

Energies
The gradual replacement of conventional generators with variable renewable energy sources (RES) will reduce their online frequency regulation (FR) resources and degrade their overall frequency control capabilities.
Chakka Bapi Ayyappa Raju, Sanjoy Debbarma, Rayapudi Srinivasa Rao   +2 more
doaj   +1 more source

Practical applications of multi-agent systems in electric power systems

, 2011
The transformation of energy networks from passive to active systems requires the embedding of intelligence within the network. One suitable approach to integrating distributed intelligent systems is multi-agent systems technology, where components of ...
Mcarthur, Stephen, Euan M. Davidson, Catterson, Victoria, Victoria M. Catterson, Davidson, Euan, Stephen D. J. McArthur   +5 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

An AI-Layered with Multi-Agent Systems Architecture for Prognostics Health Management of Smart Transformers: A Novel Approach for Smart Grid-Ready Energy Management Systems

Energies, 2022
After the massive integration of distributed energy resources, energy storage systems and the charging stations of electric vehicles, it has become very difficult to implement an efficient grid energy management system regarding the unmanageable behavior
Oussama Laayati, Hicham El Hadraoui, Adila El Magharaoui, Nabil El-Bazi, Mostafa Bouzi, Ahmed Chebak, Josep M. Guerrero   +6 more
doaj   +1 more source

Dynamic voltage control of a smart distribution transformer

, 2016
With the increased penetration of distributed generation, maintaining voltages across distribution networks within statutory limits becomes challenging. To maintain the voltage within statutory limits with the variability of the distributed generation, a
Binduhewa, P. J., Abeyratne, S. G., Ekanayake, Janaka, Wijayaratne, L.   +3 more
core   +1 more source

Mixed H₂/H_∞ Optimal Voltage Control Design for Smart Transformer Low-Voltage Inverter

, 2022
The smart transformer has been widely applied for the integration of renewables and loads. For the smart transformer application, the voltage control of low-voltage inverter is important for feeding the load. In this paper, a multi-objective optimization
Zhichun Yang, Huaidong Min, Wei Hu, Yu Shen   +3 more
core   +1 more source