Results 81 to 90 of about 210,928 (270)

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Hubungan Kelentukan Pergelangan Tangan dan Tinggi Lompatan dengan Hasil Smash Bola Voli Pemain Bola Voli Tim Himadirga Unsyiah [PDF]

, 2016
Penelitian ini bertujuan untuk mengetahui hubungan kelentukan pergelangan tangan dan tinggi lompatan dengan hasil smash bola voli pemain bola voli Tim Himadirga Unsyiah. Jenis penelitian termasuk dalam penelitian korelasi.
Bustamam, B. (Bustamam), Ifwandi, I. (Ifwandi), Saputra, M. (Mirja)   +2 more
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Partial actions of weak Hopf algebras: smash products, globalization and Morita theory

, 2015
In this paper we introduce the notion of partial action of a weak Hopf algebra on algebras, unifying the notions of partial group action [11], partial Hopf action ([2],[3],[9]) and partial groupoid action [4].
Castro, Felipe, Paques, Antonio, Quadros, Glauber, Sant'Ana, Alveri   +3 more
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

KONTRIBUSI DAYA LEDAK LENGAN DAN KELENTUKAN TOGOK KE BELAKANG TERHADAP KEMAMPUAN SMASH DALAM PERMAINAN BULUTANGKIS PADA ATLET BKMF BULUTANGKIS FIK UNM [PDF]

, 2015
: Smash is one form of attack that can killthe opponent's defense as well as to obtain the value or point. In the game of badminton, smash is one technique that plays an important role, failed and successful team in the game or match is determined by the
H., Herman
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Precision matrix expansion - efficient use of numerical simulations in estimating errors on cosmological parameters

, 2017
Computing the inverse covariance matrix (or precision matrix) of large data vectors is crucial in weak lensing (and multi-probe) analyses of the large scale structure of the universe.
Eifler, Tim, Friedrich, Oliver
core   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Faktor Anthropometri Dan Fisik Dominan Penentu Ketepatan Smash Bulutangkis pada Club PB. FIK Uncen

Multilateral: Jurnal Pendidikan Jasmani dan Olahraga
Badminton adalah olahraga yang populer di Indonesia, termasuk di Kota Jayapura, di mana PB. FIK Uncen berperan aktif dalam pembinaan atlet berbakat. Pencapaian prestasi dalam bulu tangkis sangat bergantung pada penguasaan teknik, dengan salah satu teknik
Evi Sinaga, Junalia Muhammad, Nasruddin Nasruddin, Yulia Cinta Ramadhani, Miftah Fariz Prima Putra   +4 more
doaj   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Pengaruh Kemampuan Fisik Terhadap Keterampilan Smash Dalam Cabang Olahraga Bulutangkis Anggota Club Bulutangkis ICLI Gowata Sungguminasa Kabupaten Gowa [PDF]

, 2017
Penelitian ini adalah jenis penelitian Ex Post Facto yang bertujuan untuk mengetahui: (1) Apakah ada pengaruh fleksibitas pergelangan tangan terhadap keterampilam smash dalam olahraga bulutangkis.
WAHAB, WAIS AULIYAH
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