Results 221 to 230 of about 536,687 (331)

Discovery of a Phenylalanine‐Derived Natural Compound as a Potential Dual Inhibitor of MDM2 and MDMX

ChemMedChem, EarlyView.
P5, a novel phenylalanine‐derived compound isolated from Micromonospora sp. MS‐62, exhibits dual inhibition of MDM2 and MDMX. Molecular docking and SPR confirm its nanomolar affinity and sustained binding kinetics. In silico profiling reveals high GI absorption, BBB permeability, and drug‐likeness, highlighting its potential as a lead for p53‐targeted ...
Ja Young Cho, Sanghwa Park, Taejung Kim, Junghye Eom, Jung‐Rae Rho, Hyoung‐Woo Bai   +5 more
wiley   +1 more source

To Smile and Not to Smile

Social Analysis, 2018
openaire   +2 more sources

DDGP versus SMILE in Newly Diagnosed Advanced Natural Killer/T-Cell Lymphoma: A Randomized Controlled, Multicenter, Open-label Study in China

Clinical Cancer Research, 2016
Xin Li, Yingying Cui, Zhenchang Sun, Lei Zhang, Ling Li, Xinhua Wang, Jingjing Wu, Xiaorui Fu, Wang Ma, Xudong Zhang, Y. Chang, F. Nan, Wencai Li, L. Su, Jinghua Wang, Hongwei Xue, Mingzhi Zhang   +16 more
semanticscholar   +1 more source

A smile [PDF]

, 2003
Nathaniel H. Robin
openalex   +1 more source

An Efficient Method Using Small‐Sized Datasets Based upon Generative Adversarial Networks: Investigation of Cluster Configuration Space

Chemistry–Methods, EarlyView.
An efficient method based on generative adversarial networks is proposed using small‐sized datasets. The atomic and molecular cluster configuration spaces are investigated to show the generation ability of the proposed method. Benchmark results demonstrate superior performance over the widely used genetic algorithms.
Jintao Xie, Qing Lu, Wensheng Bian
wiley   +1 more source

Symptom Onset in Classic Rett Syndrome: Analysis of Initial Clinical Severity Scale Entries

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Objective We aim to assess the clinical features of Rett syndrome (RTT) at registration into the National Institutes of Health–sponsored natural history study (NHS) using the Clinical Severity Scale (CSS). Introduction The CSS was established in 2000 to assess characteristics of individuals with RTT and related disorders.
Alan K. Percy, Jeffrey L. Neul, Amitha Ananth, Timothy A. Benke, Eric D. Marsh   +4 more
wiley   +1 more source

Global Surgery Speaker Series: An Education and Advocacy Resource for the Advancement of Global Plastic Surgery

Plastic and Reconstructive Surgery, Global Open
Umutoni Alice, MBChB, Ulrick Sidney Kanmounye, MD, Desmond T. Jumbam, MSc, Ruben Ayala, MD, MSc   +3 more
doaj   +1 more source

[Studies of rearrangement reactions. X. Smiles rearrangement on pyridine derivatives. 7].

, 1965
Y. MAKI, Makoto Sato, Kazuko Yamane
openalex  

Semi‐Automated Pipeline for Transition State Search of Molecular Photoswitches

ChemPhotoChem, EarlyView.
A semi‐automated pipeline for the transition state search of molecular switches (PiTS3) is reported, which facilitates the search, optimization, and conformational analysis of transition states of photochemical switches based on the stilbene, imine, aza‐diarylethene, and norbornadiene structures.
Roman Yu. Peshkov, Jorn D. Steen, Stefano Crespi   +2 more
wiley   +1 more source

Smile analysis [PDF]

, 2003
Stanley P. Kessel
openalex   +1 more source