Results 101 to 110 of about 34,035 (308)

Cost‐effectiveness of DPYD genotyping prior to fluoropyrimidine‐based treatment for colorectal cancer in Wales

British Journal of Clinical Pharmacology, EarlyView.
Abstract Background Regulatory guidance in the United Kingdom advises DPYD genotyping prior to fluoropyrimidine‐based treatment. This economic evaluation estimated the costs and outcomes associated with DPYD screening prior to prescribing fluoropyrimidines for colorectal cancer in Wales and also considers additional variants to those included in ...
Catrin O. Plumpton, Sian M. Morgan, Richard A. Adams, Samantha Cox, Angharad A. Rudkin, Megan Fealey, Craig Barrington, Michelle D. Wood, Dyfrig A. Hughes   +8 more
wiley   +1 more source

sj-pdf-1-smm-10.1177_09622802211038754 - Supplemental material for Revisiting performance metrics for prediction with rare outcomes

, 2021
Supplemental material, sj-pdf-1-smm-10.1177_09622802211038754 for Revisiting performance metrics for prediction with rare outcomes by Samrachana Adhikari, Sharon-Lise Normand, Jordan Bloom, David Shahian and Sherri Rose in Statistical Methods in Medical ...
David Shahian (10272136), Sherri Rose (21483), Jordan Bloom (11377219), Samrachana Adhikari (7818143), Sharon-Lise Normand (5880047)   +4 more
core   +1 more source

Monitoring pharmacodynamic and molecular drug targets in liquid biopsy: Exploratory study in liver cancer with modelling of EGFR Receptor engagement

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Liquid biopsy is minimally invasive (compared with tissue biopsy) and has previously been used to generate systems data regarding drug elimination via hepatic enzymes and transporters. This study extends quantitative assessment of systems parameters in liquid biopsy to pharmacodynamic (PD) and disease markers relevant to cancer development
Zubida M. Al‐Majdoub, Armin Sepp, Amin Rostami‐Hodjegan, Brahim Achour   +3 more
wiley   +1 more source

MARKETING MANAGEMENT IN SMM [PDF]

Investytsiyi: praktyka ta dosvid, 2021
R. Bezus, L. Kryuchko, K. Pererva
openaire   +1 more source

sj-pdf-1-smm-10.1177_09622802221122427 - Supplemental material for Robust integrative biclustering for multi-view data

, 2022
Supplemental material, sj-pdf-1-smm-10.1177_09622802221122427 for Robust integrative biclustering for multi-view data by Weijie Zhang, Christine Wendt, Russel Bowler, Craig P Hersh and Sandra E Safo in Statistical Methods in Medical ...
Craig P Hersh (8414697), Sandra E Safo (13801657), Russel Bowler (13801654), Weijie Zhang (145595), Christine Wendt (127579)   +4 more
core   +1 more source

Adaptive imatinib regimens can mitigate cumulative toxicity while sustaining hemodynamic benefit: A model‐based simulation of the positioning imatinib for pulmonary arterial hypertension trial

British Journal of Clinical Pharmacology, EarlyView.
ABSTRACT Aims Imatinib improves hemodynamics in pulmonary arterial hypertension (PAH), but dose‐dependent toxicity has limited its clinical development. We aimed to quantify the dose–efficacy–toxicity relationship and evaluate alternative dosing strategies using data from the PIPAH trial.
Medhat M. Said, Robert B. de Mooij, Dian Jiao, Reitze J. Ovelgonne, Rami Biram, Juan Delgado‐SanMartin, Alexander M. K. Rothman, Sofia S. Villar, Andreas A. Roussakis, Jurjan Aman, Ron A. A. Mathôt, Eleonora L. Swart, Martin R. Wilkins, Imke H. Bartelink   +13 more
wiley   +1 more source

sj-pdf-1-smm-10.1177_09622802211047346 - Supplemental material for Multiple imputation with missing data indicators

, 2021
Supplemental material, sj-pdf-1-smm-10.1177_09622802211047346 for Multiple imputation with missing data indicators by Lauren J Beesley, Irina Bondarenko, Michael R Elliot, Allison W Kurian, Steven J Katz and Jeremy MG Taylor in Statistical Methods in ...
Michael R Elliot (11563847), Steven J Katz (11563853), Allison W Kurian (11563850), Irina Bondarenko (9225985), Lauren J Beesley (11563844), Jeremy MG Taylor (10689046)   +5 more
core   +1 more source

An Indicator‐Based Decision Framework for Circular Bioeconomy Transition in the Steel Industry: Integrating Multiphase Learning and Cooperative Game Modelling

Business Strategy and the Environment, EarlyView.
ABSTRACT Despite growing attention to the circular bioeconomy (CBE), the steel industry currently lacks a standardised, sectoral measurement framework to facilitate a low‐carbon transition. In this study, a decision‐support framework for evaluating CBE performance in the steel industry is proposed.
Ali Zamani Babgohari, Mohammadreza Sadeghi‐Moghadam, Hannan Amoozad Mahdiraji   +2 more
wiley   +1 more source

sj-pdf-1-smm-10.1177_0962280215586456 - Supplemental material for A multistate additive relative survival semi-Markov model

, 2015
Supplemental material, sj-pdf-1-smm-10.1177_0962280215586456 for A multistate additive relative survival semi-Markov model by Florence Gillaizeau, Etienne Dantan, Magali Giral, Yohann Foucher, Professor Marie Davidian in Statistical Methods in Medical ...
Florence Gillaizeau (424323), Magali Giral (221237), Yohann Foucher (216553), Etienne Dantan (4913494), Marie Davidian (3212625)   +4 more
core   +1 more source

sj-pdf-1-smm-10.1177_09622802221129040 - Supplemental material for Revisiting Gaussian Markov random fields and Bayesian disease mapping

, 2022
Supplemental material, sj-pdf-1-smm-10.1177_09622802221129040 for Revisiting Gaussian Markov random fields and Bayesian disease mapping by Ying C MacNab in Statistical Methods in Medical ...
Ying C MacNab (14042641)
core   +1 more source