Results 1 to 10 of about 4,307,039 (298)

Impact of Skeletal Muscle Mass on Metabolic Health [PDF]

Endocrinology and Metabolism, 2020
Skeletal muscle is regarded as an endocrine and paracrine organ. Muscle-derived secretory proteins, referred to as myokines, mediate interactions between skeletal muscle mass and other organs such as the liver, adipose tissue, pancreas, bone, and the ...
Gyuri Kim, Jae Hyeon Kim
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Pharmacological inhibition of lipolysis prevents adverse metabolic outcomes during glucocorticoid administration

Molecular Metabolism, 2023
Objective: Glucocorticoids are one of the most commonly prescribed classes of anti-inflammatory drugs; however, chronic treatment promotes iatrogenic (drug-induced) diabetes.
Melissa A. Linden, Susan J. Burke, Humza A. Pirzadah, Tai-Yu Huang, Heidi M. Batdorf, Walid K. Mohammed, Katarina A. Jones, Sujoy Ghosh, Shawn R. Campagna, J. Jason Collier, Robert C. Noland   +10 more
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Dietary Fiber Intake Is Related to Skeletal Muscle Mass, Body Fat Mass, and Muscle-to-Fat Ratio Among People With Type 2 Diabetes: A Cross-Sectional Study

Frontiers in Nutrition, 2022
ObjectivesTo investigate the relationship between dietary fiber intake and skeletal muscle mass, body fat mass, and muscle-to-fat ratio (MFR) among men and women with type 2 diabetes (T2D).MethodsThis cross-sectional study involved 260 men and 200 women ...
Fuyuko Takahashi, Yoshitaka Hashimoto, Ayumi Kaji, Ryosuke Sakai, Yuka Kawate, Takuro Okamura, Hiroshi Okada, Noriyuki Kitagawa, Noriyuki Kitagawa, Naoko Nakanishi, Saori Majima, Takafumi Osaka, Takafumi Senmaru, Emi Ushigome, Mai Asano, Masahide Hamaguchi, Masahiro Yamazaki, Michiaki Fukui   +17 more
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Skeletal muscle loss is an independent negative prognostic factor in patients with advanced lower rectal cancer treated with neoadjuvant chemoradiotherapy. [PDF]

PLoS ONE, 2018
The impact of body composition on the short- or long-term outcomes of patients with surgically treated advanced rectal cancer after neoadjuvant chemoradiotherapy remains unclear.
Yasuhiro Takeda, Takashi Akiyoshi, Kiyoshi Matsueda, Hironori Fukuoka, Atsushi Ogura, Hisanori Miki, Yukiharu Hiyoshi, Toshiya Nagasaki, Tsuyoshi Konishi, Yoshiya Fujimoto, Yosuke Fukunaga, Masashi Ueno   +11 more
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Low skeletal muscle mass is associated with increased hospital expenditure in patients undergoing cancer surgery of the alimentary tract. [PDF]

PLoS ONE, 2017
Low skeletal muscle mass is associated with poor postoperative outcomes in cancer patients. Furthermore, it is associated with increased healthcare costs in the United States.
Jeroen L A van Vugt, Stefan Buettner, Stef Levolger, Robert R J Coebergh van den Braak, Mustafa Suker, Marcia P Gaspersz, Ron W F de Bruin, Cornelis Verhoef, Casper H C van Eijck, Niek Bossche, Bas Groot Koerkamp, Jan N M IJzermans   +11 more
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Postoperative Loss of Skeletal Muscle Mass Predicts Poor Survival After Gastric Cancer Surgery

Frontiers in Nutrition, 2022
BackgroundSkeletal muscle mass deterioration is common in gastric cancer (GC) patients and is linked to poor prognosis. However, information regarding the effect of skeletal muscle mass changes in the postoperative period is scarce.
Shanjun Tan, Qiulin Zhuang, Zhige Zhang, Shuhao Li, Jiahao Xu, Junjie Wang, Yanni Zhang, Qiulei Xi, Qingyang Meng, Yi Jiang, Guohao Wu   +10 more
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Role of microRNAs in skeletal muscle hypertrophy

Frontiers in Physiology, 2014
Skeletal muscle comprises approximately 40% of body weight, and is important for locomotion, as well as for metabolic homeostasis. Adult skeletal muscle mass is maintained by a fine balance between muscle protein synthesis and degradation. In response to
Keisuke eHitachi, Kunihiro eTsuchida
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mTOR as a Key Regulator in Maintaining Skeletal Muscle Mass

Frontiers in Physiology, 2017
Maintenance of skeletal muscle mass is regulated by the balance between anabolic and catabolic processes. Mammalian target of rapamycin (mTOR) is an evolutionarily conserved serine/threonine kinase, and is known to play vital roles in protein synthesis ...
Mee-Sup Yoon
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p21-Activated Kinase 1 Is Permissive for the Skeletal Muscle Hypertrophy Induced by Myostatin Inhibition

Frontiers in Physiology, 2021
Skeletal muscle, the most abundant tissue in the body, plays vital roles in locomotion and metabolism. Understanding the cellular processes that govern regulation of muscle mass and function represents an essential step in the development of therapeutic ...
Caroline Barbé, Audrey Loumaye, Pascale Lause, Olli Ritvos, Jean-Paul Thissen   +4 more
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Greater lean tissue and skeletal muscle mass are associated with higher bone mineral content in children

Nutrition & Metabolism, 2010
Background To compare the relationship of skeletal muscle mass with bone mineral content in an ethnically diverse group of 6 to 18 year old boys and girls. Methods 175 healthy children (103 boys; 72 girls) had assessments of body mass, height, and Tanner
Thornton John C, Dorsey Karen B, Heymsfield Steven B, Gallagher Dympna   +3 more
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