Results 41 to 50 of about 4,307,039 (298)

Differential response of skeletal muscles to mTORC1 signaling during atrophy and hypertrophy [PDF]

, 2013
BACKGROUND: Skeletal muscle mass is determined by the balance between protein synthesis and degradation. Mammalian target of rapamycin complex 1 (mTORC1) is a master regulator of protein translation and has been implicated in the control of muscle mass ...
Handschin, Christoph, Bentzinger, C. Florian, Guridi, Maitea, Castets, Perrine, Hall, Michael N, Tintignac, Lionel A., Hall, Michael N., Perrine Castets, Romanino, Klaas, Tintignac, Lionel, Rüegg, Markus A, Michael N Hall, Lin, Shuo, Markus A Rüegg, Bentzinger, C Florian, Christoph Handschin, Serge Summermatter, Summermatter, Serge, C Bentzinger, Klaas Romanino, Maitea Guridi, Shuo Lin, Rüegg, Markus A., Lionel A Tintignac   +23 more
core   +1 more source

Molecular regulation of skeletal muscle mass and the contribution of nitric oxide: A review

FASEB BioAdvances, 2019
A variety of internal and external factors such as exercise, nutrition, inflammation, and cancer‐associated cachexia affect the regulation of skeletal muscle mass.
Jun Kobayashi, Hiroyuki Uchida, Ayaka Kofuji, Junta Ito, Maki Shimizu, Hyounju Kim, Yusuke Sekiguchi, Seiji Kushibe   +7 more
doaj   +1 more source

Regulation of Skeletal Muscle Oxidative Capacity and Muscle Mass by SIRT3

PLoS ONE, 2014
We have previously reported that the expression of mitochondrial deacetylase SIRT3 is high in the slow oxidative muscle and that the expression of muscle SIRT3 level is increased by dietary restriction or exercise training. To explore the function of SIRT3 in skeletal muscle, we report here the establishment of a transgenic mouse model with muscle ...
Lin, Ligen G., Chen, Keyun. Y., Abdel Khalek, Waed, Ward, Jack Lee Iii, Yang, Henry, Chabi, Béatrice, Cabello, Chantal, Tong, Qiang   +7 more
openaire   +7 more sources

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Enhancement of K+ conductance improves in vitro the contraction force of skeletal muscle in hypokalemic periodic paralysis [PDF]

, 1990
An abnormal ratio between Na+ and K+ conductances seems to be the cause for the depolarization and paralysis of skeletal muscle in primary hypokalemic periodic paralysis.
Quasthoff, Stefan, Lehmann-Horn, Frank, Strupp, Michael, Grafe, Peter, Frank Lehmann-Horn, Peter Grafe, Stefan Quasthoff, Michael Strupp   +7 more
core   +1 more source

Association between body composition and bone mineral density in community-dwelling older adults from Chile: a sex-stratified DXA-based cross-sectional study

BMC Geriatrics
Introduction Decreased bone mineral density (BMD) remains one of the main determinants of frailty and fracture risk in older adults. Lean mass is an important contributor to bone health through mechanical loading and muscle–bone interactions ...
Nicole Fritz-Silva, Cristian Mansilla-Antilef, María Angélica Castillo-Cerda, Carla Bittner-Hofmann, Carol Ule-Marín   +4 more
doaj   +1 more source

Skeletal muscle reference for Chinese children and adolescents

Journal of Cachexia, Sarcopenia and Muscle, 2019
Background Skeletal muscle as an essential body composition component plays an important role in maintenance of normal growth and development as well as systemic glucose metabolism in children.
Junting Liu, Yinkun Yan, Bo Xi, Guimin Huang, Jie Mi, on behalf of China Child and Adolescent Cardiovascular Health (CCACH) Study Group   +5 more
doaj   +1 more source

Activation of the dopamine 1 and dopamine 5 receptors increase skeletal muscle mass and force production under non-atrophying and atrophying conditions

BMC Musculoskeletal Disorders, 2011
Background Control of skeletal muscle mass and force production is a complex physiological process involving numerous regulatory systems. Agents that increase skeletal muscle cAMP levels have been shown to modulate skeletal muscle mass and force ...
Dietrich Jeffrey A, Dolan Elizabeth T, Lefever Frank R, Hinkle Richard T, Reichart Deborah L, Sibley David R, Isfort Robert J   +6 more
doaj   +1 more source

Relationship between the skeletal muscle mass index and physical activity of Japanese children: A cross-sectional, observational study.

PLoS ONE, 2021
Regular physical activity is an important component of physical health of children and has been associated with increasing skeletal muscle mass and muscle strength.
Tadashi Ito, Hideshi Sugiura, Yuji Ito, Koji Noritake, Nobuhiko Ochi   +4 more
doaj   +1 more source

The Functional Role of Long Non-Coding RNA in Myogenesis and Skeletal Muscle Atrophy

Cells, 2022
Skeletal muscle is a pivotal organ in humans that maintains locomotion and homeostasis. Muscle atrophy caused by sarcopenia and cachexia, which results in reduced muscle mass and impaired skeletal muscle function, is a serious health condition that ...
Keisuke Hitachi, Masahiko Honda, Kunihiro Tsuchida   +2 more
doaj   +1 more source