Results 31 to 40 of about 4,307,039 (298)
The role of mTORC1 in the regulation of skeletal muscle mass
Faculty Reviews, 2022 Skeletal muscle mass is a very plastic characteristic of skeletal muscle and is regulated by signaling pathways that control the balance between anabolic and catabolic processes. The serine/threonine kinase mechanistic/mammalian target of rapamycin (mTOR) has been shown to be critically important in the regulation of skeletal muscle mass through its ...
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Journal of Cachexia, Sarcopenia and Muscle, 2022 Low skeletal muscle mass is known to be associated with poor morbidity and mortality outcomes in cancer, but evidence of its impact on health‐related quality of life (HRQOL) is less established.
Lauren Hanna +4 more
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Haemodynamic responses to heat stress and hypohydration in resting and exercising humans: Implications for the regulation of skeletal muscle blood flow [PDF]
, 2010 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Heat stress-induced hyperthermia and exercise-induced hypohydration are associated with marked alterations in limb and systemic haemodynamics in humans ...
Pearson, James
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Feasibility of using chest computed tomography (CT) imaging at the first lumbar vertebra (L1) level to assess skeletal muscle mass: a retrospective study [PDF]
PeerJ, 2023 Background Skeletal muscle mass is an essential parameter for diagnosing sarcopenia. The gold standard for assessing skeletal muscle mass is using computed tomography (CT) to measure skeletal muscle area at the third lumbar vertebra (L3) level.
Shaohua Liu +7 more
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MICU3 regulates mitochondrial Ca2+-dependent antioxidant response in skeletal muscle aging
Cell Death and Disease, 2021 Age-related loss of skeletal muscle mass and function, termed sarcopenia, could impair the quality of life in the elderly. The mechanisms involved in skeletal muscle aging are intricate and largely unknown.
Yun-Fei Yang +10 more
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LINCing Nuclear Mechanobiology With Skeletal Muscle Mass and Function [PDF]
Frontiers in Cell and Developmental Biology, 2021 Skeletal muscle demonstrates a high degree of adaptability in response to changes in mechanical input. The phenotypic transformation in response to mechanical cues includes changes in muscle mass and force generating capabilities, yet the molecular pathways that govern skeletal muscle adaptation are still incompletely understood.
Maria J. A. van Ingen, Tyler J. Kirby
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Age and Ageing, 2022 AbstractBackgroundSarcopenia is assessed by several methods, including dual energy X-ray absorptiometry (DEXA), which provide a height-adjusted skeletal muscle index (H-SMI). A SMI 2 standard deviation below the young adult reference [1] combined with low muscle strength or performance is used to identify sarcopenia.
Yee, Ming Li +3 more
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The transcriptional coactivator PGC-1α is dispensable for chronic overload-induced skeletal muscle hypertrophy and metabolic remodeling [PDF]
, 2013 Skeletal muscle mass loss and dysfunction have been linked to many diseases. Conversely, resistance exercise, mainly by activating mammalian target of rapamycin complex 1 (mTORC1), promotes skeletal muscle hypertrophy and exerts several therapeutic ...
Handschin, Christoph +9 more
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Cardiovascular Diabetology, 2018 Background Skeletal muscle mass was negatively associated with metabolic syndrome prevalence in previous cross-sectional studies. The aim of this study was to investigate the impact of baseline skeletal muscle mass and changes in skeletal muscle mass ...
Gyuri Kim +10 more
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Lipid modulation of skeletal muscle mass and function
Journal of Cachexia, Sarcopenia and Muscle, 2016 AbstractLoss of skeletal muscle mass is a characteristic feature of various pathologies including cancer, diabetes, and obesity, as well as being a general feature of ageing. However, the processes underlying its pathogenesis are not fully understood and may involve multiple factors.
Lipina, Christopher, Hundal, Harinder S.
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