Results 151 to 160 of about 33,891 (338)

Injury in Ireland [PDF]

open access: yes, 2001
Injury mortality is the fourth commonest cause of death in Ireland. The treatment of injuries has a major impact on our hospitals and on our budget for health. Long term disability following accidents is a serious problem.
Fitzpatrick, P.   +4 more
core  

Optimizing Donor Kidneys During Normothermic Machine Perfusion With Sevoflurane: Design of a Research Model

open access: yesArtificial Organs, EarlyView.
A stable kidney normothermic machine perfusion model with sevoflurane delivery via a vaporizer was established, enabling mechanistic and therapeutic studies of ischemia–reperfusion injury. ABSTRACT Normothermic machine perfusion (NMP) of donor kidneys provides an opportunity not only for organ preservation but also for therapeutic intervention to ...
Philip N. Günkel   +10 more
wiley   +1 more source

An early HMGB1 rise 12 hours before creatinine predicts acute kidney injury and multiple organ failure in a smoke inhalation and burn swine model

open access: yesFrontiers in Immunology
BackgroundAcute kidney injury (AKI) and multiple organ failure (MOF) are leading causes of mortality in trauma injuries. Early diagnosis of AKI and MOF is vital to improve outcomes, but current diagnostic criteria rely on laboratory markers that are ...
Zhangsheng Yang   +7 more
doaj   +1 more source

Characteristics of Women, Intrapartum Interventions, and Maternal and Neonatal Outcomes Among Users of Intrapartum Water Immersion: The UK POOL Cohort Study

open access: yesBirth, EarlyView.
ABSTRACT Background The POOL study explored intrapartum water immersion and associated maternal and neonatal outcomes at 26 UK sites 2015–2022. Methods Retrospective and prospective data captured in electronic maternity and neonatal UK National Health Service (NHS) information systems. Analysis—(a) proportions of women using and factors associated with
Julia Sanders   +15 more
wiley   +1 more source

Barnes Hospital Bulletin [PDF]

open access: yes, 1986
https://digitalcommons.wustl.edu/bjc_barnes_bulletin/1240/thumbnail ...

core   +1 more source

Psychedelics as pharmacotherapeutics for substance use disorders: A scoping review on clinical trials and perspectives on underlying neurobiology

open access: yesBritish Journal of Pharmacology, EarlyView.
Theorized mechanism of dopamine homeostasis restoration in the nucleus accumbens core induced by a psychedelic intervention. Abstract Psychedelics have garnered great attention in recent years as treatments for major depressive disorder (MDD) and treatment‐resistant depression because of their ability to alter consciousness and afflicted cognitive ...
Lucas Wittenkeller   +3 more
wiley   +1 more source

Effects of simvastatin on iNOS and caspase‑3 levels and oxidative stress following smoke inhalation injury. [PDF]

open access: yesMol Med Rep, 2020
Yang RQ   +8 more
europepmc   +1 more source

Cytochrome P450 1A1 influences obesity‐induced pulmonary hypertension

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose The contribution of obesity to pulmonary arterial hypertension (PAH) pathophysiology remains poorly understood. Adipose tissue synthesises estrogens via cytochrome P450 (CYP) 19A1 (aromatase), whereas circulating estrogens are metabolised in the lung by CYP1A1.
Joshua P. Dignam   +12 more
wiley   +1 more source

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