Results 71 to 80 of about 263 (200)
ABSTRACT Cadmium (Cd) is a persistent environmental heavy metal and a major public health concern because it persists in the body for long periods and gradually accumulates in vital organs, particularly the liver, kidneys, and brain. Chronic Cd exposure promotes the excessive production of reactive oxygen species (ROS), which ultimately leads to ...
Soumaya Ghodbane +8 more
wiley +1 more source
Abstract Background and aims Tobacco‐free nicotine pouches (NPs) are oral nicotine products promoted by manufacturers and some researchers as tools that may reduce nicotine cravings and support smoking reduction or cessation. However, evidence regarding their actual clinical impact remains limited.
Javad Heshmati +6 more
wiley +1 more source
Abstract Background and aims Oral nicotine pouches (ONPs) have seen a dramatic rise in sales since their introduction to the US market in 2016. We aimed to define the relationship between ONP prices and sales (e.g. price elasticity of demand) and determine how taxes on cigarettes and e‐cigarettes (ECs) impact ONP sales.
Yanyun He +7 more
wiley +1 more source
Abstract Background and aims Cocaine use disorder (CUD) is an increasingly widespread concern worldwide. Various pharmacological treatments have been investigated for CUD, but their efficacy remains unclear, and none have been licensed for treatment.
Craig Paterson +13 more
wiley +1 more source
Beyond abstinence: Redefining success in cannabis use disorder treatment
Abstract Background Over two decades of pharmacotherapy research has yet to yield a consistently effective medication for cannabis use disorder (CUD), in part because clinical trials have frequently prioritized abstinence as a primary or key endpoint.
Tobias B. Atkin +3 more
wiley +1 more source
Background: Sepsis is one of the main causes of mortality in critically ill patients following progression to septic shock. To investigate the pathophysiologic changes of sepsis, we developed a novel porcine model of septic shock induced by acute ...
Shuo Wang +5 more
doaj +1 more source
SMOKE INHALATION INJURIES IN A DOG - CASE REPORT [PDF]
Smoke inhalation injuries are relatively uncommon in veterinary pathology and the current literature on spontaneous carbon monoxide intoxication in companion animals is limited. The majority of available data are derived from isolated case reports or extrapolated from human forensic studies.
Aleksic Radojkovic, Jelena +6 more
openaire +1 more source
Abstract Background and aim Substance use disorders (SUDs) contribute significantly to global social and economic burden. Breathing‐based interventions offer a low‐cost, scalable adjunct or alternative to traditional treatment, yet their effects on substance use‐related outcomes has not been systematically evaluated.
Ariel Dart Roxburgh +7 more
wiley +1 more source
IntroductionSmoke inhalation injury (SII) is the most common cause of death in burn patients who are victims of fire. The inflammatory response to smoke inhalation is an important factor leading to acute lung injury (ALI) or acute respiratory distress ...
Ziling Ding +20 more
doaj +1 more source
Abstract Background and Aims The introduction of prescribed medical cannabis in many parts of the world raises issues regarding how we conceptualise Cannabis Use Disorders (CUD). The Diagnostic Statistical Manual Version 5 (DSM5) provides a framework for ‘Prescription Cannabis Use Disorder’ (Pr‐CUD) when a person is using medical cannabis only‐as ...
Nicholas Lintzeris, Llewellyn Mills
wiley +1 more source

