Results 101 to 110 of about 105,562 (307)

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang, Lihuan Shang, Xiaochun Chen, Xiangzhan Kong, Xiaojuan Wang, Linjia Jiang, Huiying Zhao, Yafeng Zhu, Cheng Huang, Shiyi Deng, Rui Zhang, Minghui Wang, Haoming Lin, Ping‐Pui Wong   +13 more
wiley   +1 more source

A new negative air ion smoke suppression purifier for purifying fire smoke in road tunnel based on corona discharge

Results in Engineering
The enclosed environment of a road tunnel restricts the dispersion of fire smoke, leading to its rapid accumulation, which significantly hampers firefighting efforts and personnel evacuation.
Shouzhong Feng, Deyuan Kan, Zhiguo Yan, Weixing Mao, Long Zhou   +4 more
doaj   +1 more source

Flame Retardancy and Smoke Suppression of Silicone Rubber Foam with Microencapsulated Sepiolite and Zinc Borate. [PDF]

Polymers (Basel), 2023
Kang F, Tu J, Zhao H, Bai Z, Zhang T.
europepmc   +1 more source

Automatic Fire Detection: A Survey from Wireless Sensor Network Perspective [PDF]

, 2008
Automatic fire detection is important for early detection and promptly extinguishing fire. There are ample studies investigating the best sensor combinations and appropriate techniques for early fire detection.
Bahrepour, M., Havinga, P.J.M., Meratnia, N.   +2 more
core   +2 more sources

A Profile of Injuries Sustained by Firefighters: A Critical Review [PDF]

, 2019
Firefighters, along with other tactical personnel, are at a high risk of work-related physical injury above that of the private sector. The aim of this critical narrative review was to identify, critically appraise and synthesise key findings from recent
Canetti, Elisa, Orr, Robin, Schram, Ben, Simas, Vinicius   +3 more
core   +1 more source

Microglia Mitochondria Support Neuronal Maturation via Metabolic and Transcriptional Reprogramming in Human 3D In Vitro Brain Model

Advanced Science, EarlyView.
xx xx. ABSTRACT Autism Spectrum Disorder (ASD) is a neurodevelopmental condition characterized by disrupted neuronal circuit maturation. Emerging evidence implicates microglial function and mitochondrial regulation as contributors to ASD‐associated biology, yet the mechanisms linking these processes to neuronal development remain poorly defined ...
Sydney P. Sterben, Charitha C. Anamala, Sahan B. S. Kansakar, Vaishnavi Koduri, Volha Liaudanskaya   +4 more
wiley   +1 more source

Studying flame-retardancy, smoke and toxicity of fiber-reinforced composites manufactured via modified resins and metallic coatings

Hybrid Advances
This study focuses on the development of flame-retardant fiber-reinforced polymer (FRP) composites, which are typically fire-intolerant despite their excellent mechanical, chemical, and thermal properties.
Md Shafinur Murad, Abdulhammed K. Hamzat, Eylem Asmatulu, Ersin Bahçeci, Mete Bakir, Ramazan Asmatulu   +5 more
doaj   +1 more source

Mechanostimulatory Cues Determine Intestinal Fibroblast Fate and Profibrotic Remodeling in a Physiodynamic Human Gut‐on‐a‐Chip

Advanced Science, EarlyView.
A healthy gut barrier shields underlying fibroblasts from luminal shear forces, illustrating that “good fences make good neighbors.” Barrier damage exposes fibroblasts to shear stress, inducing cell death and the emergence of stress‐adapted, profibrotic fibroblasts. Sustained shear exposure promotes the formation of stiff aggregates of mechanoadapative
Soyoun Min, Nam Than, Yong Cheol Shin, Elif G. Ertugral, Chandrasekhar R. Kothapalli, Olumuyiwa Awoniyi, Hyun Jung Kim   +6 more
wiley   +1 more source

The MINER$\nu$A Data Acquisition System and Infrastructure

, 2012
MINER$\nu$A (Main INjector ExpeRiment $\nu$-A) is a new few-GeV neutrino cross section experiment that began taking data in the FNAL NuMI (Fermi National Accelerator Laboratory Neutrinos at the Main Injector) beam-line in March of 2010.
Bagby, L., Baldin, B., Bradford, R., Brooks, W. K., Caicedo, D. A. M., Castromonte, C. M., Chvojka, J., da Motta, H., Danko, I., Devan, J., Eberly, B., Felix, J., Fields, L., Fiorentini, G. A., Gago, A. M., Gingu, C., Gran, R., Harris, D. A., Hurtado, K., Lee, H., Maher, E., Manly, S., Marshall, C. M., McFarland, K. S., Mislivec, A., Mousseau, J., Olsen, J., Osmanov, B., Osta, J., Paolone, V., Perdue, G. N., Ransome, R. D., Ray, H., Rubinov, P., Salinas, C. J. Solano, Schmitz, D. W., Schulte, E. C., Simon, C., Tice, B. G., Walton, T., Wolcott, J., Zhang, D., Ziemer, B. P.   +42 more
core   +1 more source

Single‐Cell Transcriptomics Reveals FLS2‐Dependent Hypoxia Signaling and ERF13‐Mediated Transcription During flg22‐Triggered Immunity

Advanced Science, EarlyView.
This study employs sc‐RNA sequencing, genetics, and phenotyping to systematically map the cell‐type‐specific immune responses triggered by flg22. It reveals FLS2‐dependent transcriptional reprogramming in epidermal and mesophyll cells, and uncovers crosstalk between immune and hypoxia signaling pathways.
Yaping Zhou, Aizhi Qin, Mengfan Li, Qianli Zhao, Luyao Kong, Lulu Yan, Chunyang Li, Hao Liu, Yinpeng Zhang, Jiani Long, Mengyu Liao, Mengmeng Zhou, Xiaoli Fan, Baozhen Wang, Wenxuan Kang, Shui Wang, Zhixin Liu, Xuwu Sun   +17 more
wiley   +1 more source