Results 161 to 170 of about 22,861 (256)

Early and High‐Dose Glucocorticoid Use and Survival in Advanced NSCLC Receiving Immune Checkpoint Inhibitors: A Multicenter Target Trial Emulation

Clinical Pharmacology &Therapeutics, EarlyView.
Despite the immunomodulatory mechanism of immune checkpoint inhibitors (ICIs), systemic glucocorticoids are commonly used in advanced non–small cell lung cancer (NSCLC). Evidence regarding their effects on ICI outcomes is inconsistent, in part due to confounding by indication and immortal time bias.
Da Eun Lee, Geunho Lim, Minoh Ko, Mari Kim, Ji Sun Chun, Borim Lee, Miso Kim, Kwangsoo Kim, Byung Kwan Choi, Jeongmin Seo, Jin Hyoung Kang, Taehoon Ko, In‐Wha Kim, Jung Mi Oh   +13 more
wiley   +1 more source

UMOD Genotype and Clinical Outcomes in Heart Failure Patients Treated with Loop Diuretics: A UK Biobank Pharmacogenetic Cohort Study

Clinical Pharmacology &Therapeutics, EarlyView.
Uromodulin (UMOD) regulates tubular sodium handling and modulates NKCC2, the molecular target of loop diuretics (LD). Although UMOD variants have been associated with blood pressure and hypertension, their pharmacogenetic relevance in heart failure (HF) remains unknown.
Reinhold Kreutz, Pimrapat Gebert, Jingwen Luo, Paraskevi Tassopoulou, Juliane Bolbrinker, Antonios Douros   +5 more
wiley   +1 more source

Risk Perception of Military Firefighters and Brigades in Relation to Exposure to Smoke from Forest Fires in Brazil. [PDF]

Toxics
de Araujo FJM, Caldas ED.
europepmc   +1 more source

Iron and Nickel Substituted Perovskite Cobaltites for Sustainable Oxygen Evolving Anodes in Alkaline Environment

ChemSusChem, Volume 18, Issue 6, March 15, 2025.
Perovskite oxide catalysts with reduced Co content, substituted by Fe and Ni, are synthesized and studied for their activity in the oxygen evolution reaction in alkaline media. An increase in the intrinsic catalytic activity (obtained by the (RctCdl)−1 product) of the base material (Ba0.5Gd0.8La0.7Co2O6‐δ) is seen for an as high as 70 % substitution of
Henrik Petlund, Alaa Faid, Junjie Zhu, Anuj Pokle, Truls Norby, Svein Sunde, Athanasios Chatzitakis   +6 more
wiley   +1 more source

Alterations to the Bronchial Gene-Expression Effects of Tobacco Smoking in People Living With HIV. [PDF]

J Acquir Immune Defic Syndr
Lee M, Olson A, Pickering RT, Ieong MH, Kivett D, Roche S, Xiao X, Liu G, Asundi A, Lin NH, Lenburg ME.   +10 more
europepmc   +1 more source

Micro‐QuEChERS Extraction for Broad‐Spectrum LC‐QQQ‐MS Quantification of Nitazene Analogs in Plasma: A Validated Method With Casework Application

Drug Testing and Analysis, EarlyView.
Micro‐QuEChERS sample preparation coupled to LC‐QQQ‐MS enabled sensitive quantification of nitazene analogs in 100 μL of plasma. The validated method provided low detection limits and was successfully applied to an authentic intoxication case involving N‐pyrrolidino protonitazene, supporting clinical and forensic toxicology workflows.
Karla A. O. Souza, Náthaly C. B. F. Santos, Rafael Lanaro, Sara E. Walton, Alex J. Krotulski, Barry K. Logan, Mauricio Yonamine, Jose Luiz Costa   +7 more
wiley   +1 more source

Associations Between Microbial Depletion and Autonomic Dysregulation in Binge‐Eating Disorder

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective The interplay between the gut microbiome and autonomic nervous system remains unexplored in binge‐eating disorder (BED). We aimed to explore specific microbial alterations in BED and examine their potential association with cardiac vagal tone as a distinct bio‐behavioral phenotype.
Shuang Liang, Esben Strodl, Leanne Barron, Matthew Bambling, Luis Vitetta   +4 more
wiley   +1 more source

Interface-Engineered Sodium Alginate-Based Fire-Suppressing Gel: Strong Rheology and Efficient Gas-Solid Flame Retardancy via N-P Coupling. [PDF]

Gels
Gao X, Wang H, Li H, Yang J, Cao X.
europepmc   +1 more source

Circular and Bio‐Sourced Polymers for Energy Applications: Natural Feedstocks, Recycling, and Upcycling Routes

EcoEnergy, EarlyView.
This review provides a critical comparative analysis of circular and bio‐sourced polymers for energy storage, systematically evaluating natural feedstocks alongside recycling and upcycling strategies for battery components. Key structure–property–performance relationships and inherent trade‐offs between sustainability metrics and electrochemical ...
Priyank Sinha, Amul Jain, Koushik Mahata, Sanjib Banerjee   +3 more
wiley   +1 more source

An electrical fire in the operating room: lessons from a real-world emergency. [PDF]

Korean J Anesthesiol
Jung KT.
europepmc   +1 more source