Results 181 to 190 of about 22,861 (256)

Ovarian hormone deficiency enhances wood smoke-induced immune dysfunction via transcriptomic and metabolic alterations. [PDF]

Toxicol Sci
Oh M, Yazzie S, Lim E, Edeh O, McVeigh C, Bolt A, Gillette JM, Zychowski KE.   +7 more
europepmc   +1 more source

Association of COPD with adverse outcomes in heart failure patients with preserved ejection fraction

ESC Heart Failure, Volume 12, Issue 2, Page 799-808, April 2025.
Abstract We performed a systematic review and meta‐analysis to detect the impact of chronic obstructive pulmonary disease (COPD) on the prognosis of heart failure patients with preserved ejection fraction (HFpEF). We systematically screened eligible literature from three electronic databases, PubMed, EMBASE and Cochrane Library, up to April 2023.
Shuo Xu, Zhenbang Gu, Wengen Zhu, Shenghui Feng   +3 more
wiley   +1 more source

Bronchial mucosal nuclear transcription factor expression and inflammatory response in humans after exposure to wood smoke. [PDF]

Part Fibre Toxicol
Hansson A, Friberg M, Rankin G, Pourazar J, Uski O, García-López N, Boman C, Blomberg A, Behndig A, Sandström T, Muala A.   +10 more
europepmc   +1 more source

Progress report on new epilepsy treatments: A summary of the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVIII). II. Treatments in more advanced clinical development

Epilepsia, EarlyView.
Abstract This article summarizes data for 13 investigational treatments for which at least preliminary seizure outcome data in patients with epilepsy were reported at the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices held in Madrid, Spain, on May 3–6, 2026.
Meir Bialer, Cecilie Johannessen Landmark, Matthias J. Koepp, Emilio Perucca, Piero Perucca, Torbjörn Tomson, H. Steve White, Elaine Wirrell   +7 more
wiley   +1 more source

Convergent death programs in chronic obstructive pulmonary disease: how pyroptotic and ferroptotic crosstalk reshapes therapeutic paradigms. [PDF]

Front Immunol
Huang A, Liu S, Lan J.
europepmc   +1 more source

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

Epilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang, Emilio Perucca, Samuel F. Berkovic, Piero Perucca   +3 more
wiley   +1 more source

HLA-DRA-mediated inhibition of T-Cell proliferation by differentiated airway epithelium and its disruption in smoking-associated airway inflammation. [PDF]

Respir Res
Zeng J, Peng L, Yi Q, Chen X, Li X, Zhou H.   +5 more
europepmc   +1 more source

Hydrogen‐Enriched Tri‐Fuel Combustion for Low‐Carbon Engines at Medium Engine Load: A Comprehensive CFD Analysis

Energy Science &Engineering, EarlyView.
CFD analysis of a diesel–CH4–H2 tri‐fuel engine shows that increasing hydrogen energy share (HES) enhances mixing and accelerates combustion, improving pressure, efficiency, and reducing CO and soot. At 60% HES, ISFC improves 26.2%, soot drops 95%, while NOx increases due to higher temperatures. ABSTRACT The global commitment to achieve net‐zero carbon
Md. Ifthaker Alam, Tafsirul Hassan, Md Imtiaz Hossen, Md. Shaib Hossain, Bandhon Saha Bijoy   +4 more
wiley   +1 more source

Forced Draught Impact on Externally Venting Flames: An Experimental and Numerical Investigation

Fire and Materials, EarlyView.
ABSTRACT Wind can significantly influence fire development and spread in urban and forest environments causing fatal consequences for the public, the first responders, and the environment. Wind‐driven fires can have a significant impact on structural fires as wind can increase the fire's intensity, development, and flame spread.
Anoop Subramania Warrier, Jan Smolka, Kamila Kempna, Meet Panchal, Tony Graham, Eleni Asimakopoulou   +5 more
wiley   +1 more source

Update on environmental determinants of allergic diseases. [PDF]

J Allergy Clin Immunol
Monga N, Poyyakkara A, Guo Y, Gorska MM.
europepmc   +1 more source