Results 191 to 200 of about 602,024 (301)

The potential impact of H1 antihistamines on clinical outcomes in NSCLC patients undergoing EGFR‐TKIs treatment

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Background Epidermal growth factor receptor–tyrosine kinase inhibitors (EGFR‐TKIs) have substantially improved outcomes in non‐small cell lung cancer (NSCLC); however, the development of treatment resistance remains a major clinical challenge. This study examines the association between concomitant prescriptions of H1‐antihistamines (H1AHs) and ...
Van Thuan Nguyen   +10 more
wiley   +1 more source

Targeting neutrophil extracellular traps in metabolic and immune niche: Nanomaterials for diabetes tissue regeneration

open access: yesBMEMat, EarlyView.
The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang   +6 more
wiley   +1 more source

From pathogen to “living drug factory” innovative strategies and clinical translation of bacteria as programmable intelligent vectors for cancer therapy

open access: yesBMEMat, EarlyView.
Engineered bacteria serve as smart, living therapeutics that target tumors, deliver drugs, and remodel immunosuppressive microenvironments. This review highlights their potential to potentiate immunotherapy, radiotherapy, and chemotherapy, offering a promising paradigm for precise and synergistic cancer treatment. Abstract The dynamic interplay between
Haonan Shen   +9 more
wiley   +1 more source

Beyond antimicrobials: Ecological nano‐strategies for rebalancing dysbiotic oral microbial homeostasis

open access: yesBMEMat, EarlyView.
Oral microbial homeostasis, a dynamic host‐microbe balance, is vital in infectious diseases. Conventional antibiotics often disrupt this homeostasis, spurring interest in nanomaterials for oral microbial homeostasis rebalancing. This review outlines nanomaterial strategies across three ecological levels (population/community, ecosystem, and cross ...
Chen Hu   +10 more
wiley   +1 more source

What drives animal responses to high severity fire? The role of functional traits

open access: yesBiological Reviews, EarlyView.
ABSTRACT Fire regimes are changing worldwide, with increases in the frequency, extent, and severity of fires posing growing risks to biodiversity. Fire severity – the degree of habitat alteration following fire – strongly influences both immediate survival and long‐term recovery of fauna.
Grace A. Vielleux   +3 more
wiley   +1 more source

The Degradation of Access‐Based Business Models: Customer Misbehavior and Shared Mobility

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT Access‐based services are considered one of the strategies to embed sustainability in business models. Yet, because the evolution of these business models has been overlooked, we do not know whether their promise to create triple value is sustained.
Andres Camacho, Carmen Valor
wiley   +1 more source

Elucidating the Interplay Between Structure and Electrochemical Behavior in Lignin‐Based Polymer Electrolytes for Potassium Batteries

open access: yesBattery Energy, Volume 4, Issue 2, March 2025.
Three biobased membranes are synthesized by crosslinking oxidized Kraft lignin with poly(ethylene glycol) diglycidyl ether of increasing molecular weights. After incorporation of solvated potassium salts, potassium batteries including these biobased gel polymer electrolytes are able to deliver a maximum specific capacity at 0.05 A g−1 as high as 130 ...
Giuseppe Pascuzzi   +5 more
wiley   +1 more source

We ought to discuss the social construction of cadavers: Here's why and how

open access: yes
Anatomical Sciences Education, EarlyView.
Fatima Ehsan, Susan Lamb
wiley   +1 more source

Long‐term outcomes of microsurgical interdental papilla reconstruction: 13‐year and 18‐year case follow‐ups

open access: yesClinical Advances in Periodontics, EarlyView.
Abstract Background Loss of the interdental papilla compromises esthetics, speech, and hygiene, significantly affecting quality of life and psychological well‐being. Reconstruction has long been considered unpredictable, particularly in Cairo RT3 cases with advanced interproximal bone loss.
Katsuhiko Akiyama
wiley   +1 more source

Diagnostic Accuracy and Feasibility of Quantitative Flow Ratio at Low Frame Rate Angiography: The Prospective Multicentre Australian AVALON Study

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Quantitative Flow Ratio (QFR) is a well‐established, non‐hyperemic, angiographic, wire‐free predictor of ischemia when compared to Fractional Flow Reserve (FFR). However, its diagnostic accuracy at low frame rates (< 10 frames/second), commonly used in contemporary practice to minimize radiation exposure, has not been evaluated ...
Joseph M. O'Brien   +13 more
wiley   +1 more source

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