Designing a Triplet 2‐Formylphenylnitrene With Fast Tunneling Reactivity
A 3‐CF3 substituent accelerates tunneling in triplet 2‐formylphenylnitrene, making its reactivity in cryogenic matrices too fast for conventional IR spectroscopic detection. Bringing this chemistry to low‐temperature solutions allows suppression of intrinsic nitrene dimerization through faster cyclization, which even outcompetes the 1,4‐H shift ...
Sofia Braz +4 more
wiley +1 more source
Cigarette smoke and e-cigarette aerosol extracts induce myelopoiesis and suppress inflammatory cytokine production. [PDF]
Sullivan JYC +12 more
europepmc +1 more source
Abstract Organic electronics have emerged as a key class of functional materials for organic light‐emitting diodes (OLEDs), organic photovoltaics (OPVs), organic field‐effect transistors (OFETs), sensors, and printed electronics. However, commercialization remains dependent on the ability to reproducibly synthesize and manufacture high‐performance ...
Marko D. Saban, Benoît H. Lessard
wiley +1 more source
Uromodulin (UMOD) regulates tubular sodium handling and modulates NKCC2, the molecular target of loop diuretics (LD). Although UMOD variants have been associated with blood pressure and hypertension, their pharmacogenetic relevance in heart failure (HF) remains unknown.
Reinhold Kreutz +5 more
wiley +1 more source
Formononetin Alleviates Cigarette Smoke Extract-Induced Lung Injury in Mice with Gut Microbiota and Taurine/SLC6A6/NF-κB Modulation. [PDF]
Ma Z +7 more
europepmc +1 more source
Toward Fit‐for‐Purpose Data for Drug Assessment in Non‐small Cell Lung Cancer: A Core Dataset
Considering the high unmet medical need in people with non‐small cell lung cancer (NSCLC), the drug assessment for targeted therapies often rely on small populations and single‐arm trials, challenging the evaluation by regulatory authorities, health technology assessment bodies (HTAb), and clinicians.
Geeske F. Grit +6 more
wiley +1 more source
Neutrophil extracellular traps in asthma and chronic obstructive pulmonary disease: pathogenic roles, and therapeutic opportunities. [PDF]
Zhang X, Dallenga T, Krauss-Etschmann S.
europepmc +1 more source
Perovskite oxide catalysts with reduced Co content, substituted by Fe and Ni, are synthesized and studied for their activity in the oxygen evolution reaction in alkaline media. An increase in the intrinsic catalytic activity (obtained by the (RctCdl)−1 product) of the base material (Ba0.5Gd0.8La0.7Co2O6‐δ) is seen for an as high as 70 % substitution of
Henrik Petlund +6 more
wiley +1 more source
Quantitative assessment of synergistic effects in push-pull tactical ventilation during nonlinear space fires. [PDF]
Wang P +5 more
europepmc +1 more source
A Biosourced and Self‐Healable Polymer Electrolyte for Potassium Batteries
A biosourced lignin‐filled gel polymer electrolyte combines suppressed crystallinity, high ionic conductivity, and UPy‐driven self‐healing for potassium batteries. The optimized formulation sustains long‐term cycling with 97.5% capacity retention after 1000 cycles and preserves electrochemical operation after intentional membrane damage.
Sabrina Trano +6 more
wiley +1 more source

