Results 181 to 190 of about 189,991 (301)

Risk of Inflammatory Bowel Disease Following Hospital‐Treated Infections and Modulatory Role of Host Genetics to Support a Multi‐Hit Pathogenesis Model

Advanced Science, EarlyView.
Hospital‐treated infections are linked to increased risk of inflammatory bowel disease in a large prospective cohort. This risk differs by infection burden, time since infection, and host immune‐genetic susceptibility. The findings support a multi‐hit pathogenesis model in which severe infection and inherited susceptibility jointly shape inflammatory ...
Haiming Zhuang, Lintao Dan, Xin Xiang, Xixian Ruan, Shuai Yuan, Jialu Yao, Jiawei Geng, Jonas F. Ludvigsson, Tian Fu, Candida Abreu, Laurent Peyrin‐Biroulet, Xue Li, Yi Xiao, Fernando Magro, Xiaoyan Wang, Jing Sun, Jie Chen   +16 more
wiley   +1 more source

Molecular Characterization, Virulence Profiling, and Antimicrobial Susceptibility of <i>Listeria monocytogenes</i> Isolated from Smoked Fish in Poland: A Preliminary Study. [PDF]

Foods
Strzałkowska ZJ, Domańska ED, Wódz K, Kizerwetter-Świda M, Chrobak-Chmiel D, Nowak T, Kwieciński P, Rosiak E, Stańczak K, Pławińska-Czarnak J.   +9 more
europepmc   +1 more source

Multiscale Coupling From Mastication to Retronasal Aroma Perception: The PG‐DTCFN Model and Multiphysics Simulation

Advanced Science, EarlyView.
Using grilled lamb skewers as a model system, this work builds a multiscale coupling framework from oral processing to retronasal aroma perception, reveals dual‐kinetic release patterns and Electroencephalogram‐characterized central encoding features, and proposes an interpretable physics‐guided deep learning model validated by multiphysics simulation,
Che Shen, Xiongfeng He, Zihao Li, Zidong Chen, Jiajin Sun, Xinyu Jiang, Yunhui Zhang, Lizhang Wu, Ran Wang, Jingnan Lu, Bo Wang, Kezhou Cai, Baocai Xu   +12 more
wiley   +1 more source

Features of low-dose CT-detected lung nodules: individuals who never smoked vs. who smoke(d) in a Chinese general population. [PDF]

Eur Radiol
Mao Y, Dorrius MD, Sidorenkov G, van Tuinen M, Yang X, Cui X, Ye Z, Vliegenthart R, de Bock GH, Heuvelmans MA.   +9 more
europepmc   +1 more source

QRICH1 Disrupts Endoplasmic Reticulum Homeostasis and Amplifies NF‐κB Signaling in Periodontal Ligament Stem Cells to Exacerbate Diabetic Periodontitis

Advanced Science, EarlyView.
QRICH1 has been established as a key factor contributing to impaired osteogenic potential and accelerated apoptosis of PDLSCs in diabetic periodontitis. QRICH1 not only significantly enhances UPR‐associated apoptotic signaling but also amplifies NF‐κB‐mediated inflammatory responses. Its inhibition restores osteogenic capacity and reduces alveolar bone
Han Li, Xiaoyu Yang, He Wang, Yunchun Kuang, Yiyao Hu, Houxuan Li, Shuhong Li, Deping Zeng, Jie Li, Jinlin Song   +9 more
wiley   +1 more source

Interactions Between e-Cigarette Use and Quit Intentions on Cigarette Smoking in Lesbian, Gay, Bisexual, Transgender, Queer, and Other Non-Heterosexual or Cisgender Individuals. [PDF]

Nicotine Tob Res
Schuler LA, Kirkpatrick MG, Wang SD, Miner A, Huh J, Pang RD.   +5 more
europepmc   +1 more source

A Panel of Circulating Exosomal sncRNAs Associated With Lung Cancer Risk up to 10 Years in Advance

Advanced Science, EarlyView.
Lung cancer is often diagnosed too late, and current screening overlooks many people at risk. In a long‐term study of smokers, a panel of small non‐coding RNAs carried in blood exosomes signals elevated lung cancer risk up to ten years before diagnosis, pointing toward a blood‐based tool for earlier risk detection.
Zhuokun Feng, Masaki Nasu, Ayman Abdul‐Ghani, Yu Chen, Shaoqiu Chen, Isam Mohd Ibrahim, Hanqiu Zhang, Lauren Higa, Zitong Gao, Hua Yang, Raphael Bueno, Loïc Le Marchand, Youping Deng   +12 more
wiley   +1 more source

Compensatory Smoking With Very Low Nicotine Content Cigarettes: A Systematic Review and Meta-Analysis.

JAMA Netw Open
Denlinger-Apte RL, Ji Z, Harwood EA, Lockhart D, Benowitz NL, Carroll DM, Cassidy RN, Colby SM, Donny EC, Gaalema DE, Hardy BW, Hatsukami DK, Heil SH, Higgins ST, Luo X, McClernon FJ, Sigmon SC, Smith TT, Strasser AA, Tidey JW, Vock DM, White CM, Wolf JM, Koopmeiners JS.   +23 more
europepmc   +1 more source

The Sensory, Chemical and Microbiological Quality of Sous-Vide Cooked Sea Bass (<i>Dicentrarchus labrax</i> Linneaus, 1758) With Liquid Smoke Flavor. [PDF]

Food Sci Nutr
Köklü R, Turan H, Altan CO, Kocatepe D, Köstekli B, Corapci B.   +5 more
europepmc   +1 more source

A Blood‐Derived Factor Rescues ALS: Platelet Factor 4 Activates OPTN‐Dependent Autophagy to Clear SOD1 Aggregates Independently of PINK1

Advanced Science, EarlyView.
Systemic platelet factor 4 (PF4) is significantly depleted in amyotrophic lateral sclerosis (ALS). Peripheral PF4 replenishment restores central proteostasis by driving OPTN‐dependent, PINK1‐independent selective autophagy in motor neurons. This intervention effectively clears toxic SOD1 aggregates, blunts glial activation, and preserves neuromuscular ...
Qingjian Xie, Yanbo Zhu, Wenhua Jiang, Haobo Xie, Yaojia Li, Mengjie Hu, Kezheng Li, Huan Yu, Yixuan Pan, Chaoyi Jiang, Xueqin Song, Dongsheng Fan, Binbin Deng   +12 more
wiley   +1 more source