Results 201 to 210 of about 189,991 (301)

Biochemically Constrained Multi‐Omics Integration Reveals Protein–Metabolite Dependencies Across Diseases

Advanced Science, EarlyView.
ProMetNet introduces a biologically constrained deep learning framework for proteo‐metabolomic integration by embedding Reactome‐derived pathway topology into neural networks. It captures non‐linear molecular dependencies and pathway‐level metabolic reorganization, enabling interpretable discrimination.
Minghui Zhao, Na Zhou, Ruotong Liu, Xiaofei Li, Jian Li, Fuzhong Xue, Qingzhen Hou   +6 more
wiley   +1 more source

Who is and who is not attempting to quit smoking? A population study in Great Britain, 2020–2026

Jackson SE, Robson D, Brown J, Notley C, Garnett C, Cox S.   +5 more
europepmc   +1 more source

Electronic nicotine delivery systems versus nicotine replacement therapies and risk of smoking relapse: evidence from a US nationwide prospective cohort (Cancer Prevention Study-3). [PDF]

BMJ Open
Westmaas JL, Landry M, Nighbor T, Xue Z, Diver RW, Patel A, Kondo KK, Asare S, Lori A, Bandi P, Nargis N.   +10 more
europepmc   +1 more source

BraMARS: An Interpretable Histopathology‐Driven Deep Learning Model for Brain Metastasis Risk Stratification in Surgically Resected Limited‐Stage SCLC

Advanced Science, EarlyView.
This study presents BraMARS, an explainable deep learning model that estimates future brain metastasis risk in surgically resected limited‐stage small‐cell lung cancer using routine H&E‐stained whole‐slide images. By linking model‐attributed spatial histopathology with clinical outcomes and proteomic programs, BraMARS provides a biologically ...
Zijian Yang, Taolue Wang, Shilong Liu, Zicheng Zhang, Yibo Zhang, Fan Yang, Bo Yu, Shuaishuai Gao, Yu Chen, Lin Yang, Meng Zhou   +10 more
wiley   +1 more source

Nitrosamine and nicotine exposure after switching from filtered to unfiltered cigarette smoking: a cross-over clinical trial. [PDF]

Tob Control
Appolon G, Oren E, Pulvers K, Romero D, Hoh E, Dodder NG, Wong J, Nynas K, Tracey L, Lemus H, Novotny TE.   +10 more
europepmc   +1 more source

Bio‐Based Polyurethanes for Sustainable and Multifunctional Applications

Advanced Science, EarlyView.
Bio‐based polyurethanes prepared from vegetable oils, lignin, and polysaccharides have attracted increasing interest as alternatives to fossil‐derived polyurethanes. This review summarizes recent progress in their chemistry, structural engineering, and advanced applications, highlighting the roles of feedstocks, chain‐segment design, dynamic covalent ...
Xin Li, Henghui Deng, Shiwei Yu, Jiawei Huang, Zehong Chen, Dawei Zhao, Chaoqun Zhang   +6 more
wiley   +1 more source

Cigarette smoking, e-cigarette, and heated tobacco product use and associated factors among a nationally representative sample of adult Malaysians: An online survey. [PDF]

Tob Induc Dis
Sreeramareddy CT, Parlan FH, Sivanandy P, Shankar PR.   +3 more
europepmc   +1 more source

Polystyrene Nanoplastics Drive β‐Cell Dedifferentiation Through Dendritic Cell‐Intrinsic MHC‐I‐Dependent Inflammatory Crosstalk

Advanced Science, EarlyView.
Polystyrene nanoplastics disrupt pancreatic immune–endocrine homeostasis by promoting MHC‐I‐associated dendritic cell activation and inflammatory crosstalk with β cells. This immune remodeling drives β‐cell dedifferentiation, impairs insulin secretion, and aggravates metabolic dysfunction, revealing a previously unrecognized immunometabolic mechanism ...
Conghui Qiao, Yuqing Song, Fang Yang, Menghui Guo, Libin Jiang, Xiaoyue Quan, Wei Wei, Xinyang Wang, Tianshu Han, Mingyuan Liu, Wenbo Jiang   +10 more
wiley   +1 more source

Modes of Preconception Cannabis Use and Prevalence of Cannabis Use Disorder. [PDF]

Cannabis
Young-Wolff KC, Cortez CA, Adams SR, Padon AA, Prochaska JJ, Brown QL, Soroosh AJ, Campbell CI, Does MB, Ansley D, Castellanos C, Asyyed AH, Green A, Nugent JR.   +13 more
europepmc   +1 more source

Open‐Shell Conjugated Polymers Enable Photothermoelectric Conversion and Detection of Short‐Wave Infrared Light

Advanced Science, EarlyView.
Efficient conversion and detection of short‐wave infrared (SWIR) photons are becoming increasingly important for emerging photonic and energy technologies. Here, we report an organic photothermoelectric device based on an open‐shell conjugated polymer that enables SWIR energy conversion and photon detection via the photothermoelectric effect.
Guan‐Lin Chen, Soonyong Lee, Shao‐Huan Hong, Jhih‐Min Lin, Han Young Woo, Cheng‐Liang Liu   +5 more
wiley   +1 more source