Results 211 to 220 of about 372,956 (314)

TP53BP2 Promotes Placental Autophagy and Preeclampsia via G9a and DNMT1 Cooperatively Modulating E2F1

Advanced Science, EarlyView.
G9a, and DNA Methyltransferase1 (DNMT1) cooperatively modulates E2F1 on the promoter of tumor suppressor p53‐binding protein 2 (TP53BP2) increased autophagy in preeclampsia. TP53BP2 promotes autophagy in trophoblasts through DNA methylation and H3K9me2‐mediated transcriptional regulation.
Nan Jiang, Shaoju Jin, Shaoying Wen, Wen Zeng, Chen Wang, Jingyu Wang, Qingyun Song, Guizhong Li, Pengzhi Yin, Yuhui Liao, Yuee Chai, Huiping Zhang, Shengchao Ma   +12 more
wiley   +1 more source

Proportionate income spent on nicotine and tobacco products and the use of untaxed cigarettes in Germany: findings from a cross-sectional survey. [PDF]

BMJ Public Health
Klosterhalfen S, Kotz D.
europepmc   +1 more source

Tobacco Smoke Exposure From Prenatal To Adolescent Periods Drives IBD Pathogenesis: Dynamic DNA Methylation Signatures Across Lifespan Stages

Advanced Science, EarlyView.
This study illustrates that maternal smoking during pregnancy (MSDP) is an independent risk factor for IBD in offspring, and DNA methylation serves as a key mechanistic pathway connecting early‐life smoking exposure with IBD risk in offspring. That highlights the urgent need for preventive interventions targeting prospective parents and minors to ...
Han Zhang, Jianhui Zhao, Jie Chen, Xinyi Ma, Siyun Zhou, Alexandra Noble, Rahul Kalla, Judith Wellens, Kun Liu, Evropi Theodoratou, Jack Satsangi, Xue Li   +11 more
wiley   +1 more source

Effect of smoking on drug-resistant tuberculosis treatment outcomes and potential mechanistic pathways: a multicountry cohort study. [PDF]

BMJ Open Respir Res
Romo ML, LaHood A, Stagg HR, Mitnick CD, Trevisi L, Hewison C, Padayachee S, Herrera Flores E, Oyewusi L, Khan PY, Huerga H, Bastard M, Rich ML, Tefera GB, Rashitov M, Kirakosyan O, Krisnanda A, Toktogonova A, Siddiqui MR, Gómez-Restrepo C, Kotrikadze T, Franke MF, endTB Observational Study Team.   +22 more
europepmc   +1 more source

Programmable Pentamolecular Cross‐Scale Imaging Reveals the Multiplicative Synergistic Effect of High‐Fat / High‐Salt Diet on Atherosclerosis

Advanced Science, EarlyView.
This study demonstrates multifactorial lifestyle impacts on the pathogenesis and progression of cardiovascular diseases by a nanofluorescence sensor array for detecting four redox species and protein phosphorylation levels. Through cross‐scale fluorescence imaging of rats with different diets, we revealed that compared with single dietary interventions,
Jin Li, Na Zhao, Mengmeng Lu, Ruize Zhao, Wei Zhang, Ping Li, Yue Tang, Wen Zhang, Hui Wang, Bo Tang   +9 more
wiley   +1 more source

History of cannabis smoking and subjective cognitive complaints in older women. [PDF]

Neuroepidemiology
Ding G, Bohnert KM, Li C, Plassman BL, Liang X, Yuan Y, D'Aloisio AA, White AJ, Sandler DP, Chen H.   +9 more
europepmc   +1 more source

Dorset Primary Care Trust - User Survey 2008 [PDF]

, 2008
Brackstone, J., Calver, S.J., Rosenorn-Lang, E.   +2 more
core  

Parasitic Plant–Host Interactions: Molecular Mechanisms and Agricultural Resistance Strategies

Advanced Science, EarlyView.
Parasitic plants devastate global agriculture through sophisticated molecular interactions with host crops. This review synthesizes current understanding of parasitic plant‐host interactions, from strigolactone‐mediated germination and haustorium formation to host defense mechanisms.
Jiayang Shi, Qi Xie, Feifei Yu
wiley   +1 more source

Young people's smoking and vaping behaviour, and comparative perceptions of appeal, imagery and harm, across different vape devices and a tobacco cigarette: findings from UK cross-sectional surveys in 2020 and 2023. [PDF]

Front Public Health
MacKintosh AM, Mitchell D, Hilton S, Smith M, Ford A.   +4 more
europepmc   +1 more source