Results 141 to 150 of about 2,151,119 (340)

Smoking and Social Interaction [PDF]

open access: yes
We study the social interaction of non-smokers and smokers as a sequential game, incorporating insights from social psychology and experimental economics into an economic model.
Lars-H.R. Siemers, Panu Poutvaara
core   +3 more sources

Mobilizing to overcome tobacco industry interference in lawmaking

open access: yesTobacco Induced Diseases, 2021
Traci Kennedy   +2 more
doaj   +1 more source

PP2Acα Deficiency in Vascular Smooth Muscle Cells Accelerates Aortic Aneurysm and Dissection by Regulating KLF4 Phosphorylation and Ubiquitination

open access: yesAdvanced Science, EarlyView.
Vascular smooth muscle cells (VSMCs)‐specific deficiency of PP2Acα exacerbates aortic aneurysm and dissection (AAD) by promoting phenotypic switching through AKT1‐mediated phosphorylation and stabilization of Kruppel‐like factor 4 (KLF4). Reduced PP2Acα enhances KLF4 ubiquitination resistance, suppressing VSMC contractile genes and accelerating aortic ...
Wei‐Peng Hu   +7 more
wiley   +1 more source

Combatting tobacco industry lobbyists in public health

open access: yesTobacco Induced Diseases, 2023
James Matheny   +5 more
doaj   +1 more source

Effectiveness of ICS/LABA and LAMA/LABA in COPD due to biomass

open access: yesERJ Open Research
Background COPD due to biomass exposure (COPD-B) is highly prevalent in low- and middle-income countries, and there are no clinical trials designed to evaluate the effectiveness of the treatments currently recommended for patients with COPD due to ...
Alejandra Ramírez-Venegas   +14 more
doaj   +1 more source

Clearing the haze? new evidence on the economic impact of smoking bans [PDF]

open access: yes
When smoking bans were debated in the past, the economic costs were seldom considered. But that's changing, as studies reveal the costs being paid by bars, restaurants and casinos, as well as by employees of these establishments.Tobacco ...
Michael R. Pakko
core  

Single‐Cell and Spatial Transcriptomic Profiling of Penile Squamous Cell Carcinoma Reveals Dynamics of Tumor Differentiation and Immune Microenvironment

open access: yesAdvanced Science, EarlyView.
This study uses single‐nucleus RNA sequencing and spatial transcriptomics to investigate penile squamous cell carcinoma (PSCC). It reveals that PSCC tumor cells mimic normal penile epithelium differentiation, independent of HPV status. The Tum_1 subtype shows basal stem‐like characteristics and promotes invasiveness. HPV‐positive basal stem‐like tumors
Hongjian Song   +37 more
wiley   +1 more source

Nrf2 Drives Epigenetic Reprogramming and Acts as the Master Regulator of KLF4 Expression and Activity in Arsenic‐Induced Transformation

open access: yesAdvanced Science, EarlyView.
Nrf2 isn't just a protector—it's a driver of cancer stemness. The study uncovers how arsenic‐activated Nrf2 directly upregulates KLF4, a key pluripotency factor, fueling oncogenic reprogramming. Through enhancer activation and self‐reinforcing loop, Nrf2 and KLF4 co‐opt gene networks linked to epithelial‐to‐mesenchymal transition and tumor growth ...
Ziwei Wang   +9 more
wiley   +1 more source

Air quality in Mexico City during the COVID-19 lockdown possibly decreased COPD exacerbations

open access: yesERJ Open Research, 2022
Francisco Montiel-Lopez   +11 more
doaj   +1 more source

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