Results 51 to 60 of about 2,607,087 (388)

The Association of Cigarette Smoking With Depression and Anxiety: A Systematic Review

open access: yesNicotine & Tobacco Research, 2016
Background: Many studies report a positive association between smoking and mental illness. However, the literature remains mixed regarding the direction of this association. We therefore conducted a systematic review evaluating the association of smoking
M. Fluharty   +3 more
semanticscholar   +1 more source

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

open access: yesMolecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim   +8 more
wiley   +1 more source

Electronic cigarette use and conventional cigarette smoking initiation among youth, United States, 2015-2016

open access: yesTobacco Induced Diseases, 2018
Background Electronic cigarettes (e-cigarettes) are the most commonly used tobacco product among U.S youth. We used cross-sectional, nationally representative data of U.S.
Satomi Odani   +3 more
doaj   +1 more source

Passive smoking indicators in Italy: does the gross domestic product matter? [PDF]

open access: yes, 2018
BACKGROUND: The aim of this study is to analyse the correlation between regional values of Gross Domestic Product (GDP) and passive smoking in Italy.
Cianfanelli, Sara   +5 more
core   +1 more source

Smoking prevalence and cigarette consumption in 187 countries, 1980-2012.

open access: yesJournal of the American Medical Association (JAMA), 2014
IMPORTANCE Tobacco is a leading global disease risk factor. Understanding national trends in prevalence and consumption is critical for prioritizing action and evaluating tobacco control progress.
Marie Ng   +11 more
semanticscholar   +1 more source

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu   +11 more
wiley   +1 more source

Validation of new predictors of mortality and BODE index variants in patients with COPD at moderate altitude

open access: yesERJ Open Research
Background COPD ranks as the third leading global cause of mortality. Despite the widespread use of the BODE index and its variants for mortality prediction, their accuracy may be affected by factors like ethnicity, altitude and regional disparities ...
Robinson Robles-Hernández   +10 more
doaj   +1 more source

Smoking in inflammatory bowel diseases: Good, bad or ugly? [PDF]

open access: yes, 2007
Smoking is an important environmental factor in inflammatory bowel disease (IBD), having different effects in ulcerative colitis (UC) and Crohn’s disease (CD).
Lakatos, László   +2 more
core   +1 more source

Individual behavioural counselling for smoking cessation.

open access: yesCochrane Database of Systematic Reviews, 2017
BACKGROUND Individual counselling from a smoking cessation specialist may help smokers to make a successful attempt to stop smoking. OBJECTIVES The review addresses the following hypotheses:1.
T. Lancaster, L. Stead
semanticscholar   +1 more source

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

open access: yesMolecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen   +12 more
wiley   +1 more source

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