Results 51 to 60 of about 2,177,937 (311)

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Vaping is associated with increased length of stay among cardiac inpatients

Tobacco Induced Diseases
Introduction The rapid increase in e-cigarette use, especially among youth, raises significant health concerns. Understanding their impact on high-risk populations, such as those with cardiovascular disease, is crucial for improving patient outcomes and ...
Javad Heshmati, Kerri-Anne Mullen, Kathryn L. Walker, Hassan Mir   +3 more
doaj   +1 more source

Tobacco tax and the illicit trade in tobacco products in New Zealand

Australian and New Zealand Journal of Public Health, 2015
Objectives: To estimate the size of illegal tobacco trade and consumption and assess the impact of tobacco tax on the illicit tobacco market in New Zealand (NZ). Methods: Data on the import and seizure of legal and illegal tobacco in NZ was obtained from
Ali Ajmal, Veng Ian U
doaj   +1 more source

Cigarette Smoking Habits Among University Students: Prevalence and Associated Factors [PDF]

, 2017
Smoking is the main cause of morbidity and mortality in the world and is estimated to kill 5 million people each year worldwide. If current patterns of tobacco consumption continue, smoking will kill more than 8 million people each year globally by the ...
Jamshed, J. (Junaid), Khan, M. M. (Muhammad), Latif, Z. (Zahid)   +2 more
core  

Maternal smoking and the risk of still birth: systematic review and meta-analysis [PDF]

, 2015
BACKGROUND: Smoking in pregnancy is known to be associated with a range of adverse pregnancy outcomes, yet there is a high prevalence of smoking among pregnant women in many countries, and it remains a major public health concern.
Ahankari, Anand, Coleman, Tim, Lewis, Sarah, Marufu, Takawira C.   +3 more
core   +3 more sources

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

To encounter the challenges of tobacco industry: concerted community effort to advocate for policy change

Tobacco Induced Diseases, 2018
Background and challenges to implementation The Hong Kong Government proposed to enhance pictorial health warnings (PHW), prominently increasing the size to 85%, since May 2015. Opposition and interference of tobacco industry (TI) was fierce.
Antonio Kwong, Vienna Lai
doaj   +1 more source

Influence of Socioeconomic Factors, Gender and Indigenous Status on Smoking in Taiwan. [PDF]

, 2016
The indigenous Austronesian minority of Taiwan is heavily affected by health disparities which may include suffering from a greater burden of the tobacco epidemic.
Hwang, Chiou-Wei, Keller, Joseph Jordan, Lin, Ching-Feng, Lo, Feng-En, Lo, Wen-Min, Lyu, Shu-Yu, Morisky, Donald E, Tsai, Liang-Ting, Yang, Chih-Chien   +8 more
core   +3 more sources

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Tailor-made smoke-free programme to clear the myths of smoking among Hong Kong elder people

Tobacco Induced Diseases, 2018
Background and challenges to implementation In Hong Kong, over 20% of the 641,300 daily smokers aged 60 years or above. Public's awareness on smoking hazards has increased in recent years.
Antonio Kwong, Vienna Lai
doaj   +1 more source