Results 31 to 40 of about 351,809 (268)

Patterns of marijuana and tobacco use associated with suboptimal self-rated health among US adult ever users of marijuana

Preventive Medicine Reports, 2017
The purpose of this study was to examine the patterns of marijuana and tobacco use and their associations with suboptimal self-rated health (SRH) among US adults who reported “ever, even once, using marijuana or hashish.” Data came from the 2009–2012 ...
James Tsai, Italia V. Rolle, Tushar Singh, Sheree L. Boulet, Timothy A. McAfee, Althea M. Grant   +5 more
doaj   +1 more source

Prevention – Passive smoking and pregnancy

European Journal of Cancer Supplements, 2013
Epidemiological studies have demonstrated that tobacco smoke is a major cause of both cancer and vascular diseases. More than 3800 chemicals are present in tobacco smoke, which may cause oxidative stress via biotransformation or by macrophage activation.
Nawrot, Tim S., Cox, Bianca, Janssen, Bram G., Plusquin, Michelle   +3 more
openaire   +3 more sources

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Advice from healthcare providers and cessation aid utilization among current smokers from 28 countries: findings from the Global Adult Tobacco Survey (GATS), 2008 - 2015

Tobacco Induced Diseases, 2018
Background The WHO Framework Convention on Tobacco Control calls for measures to reduce tobacco dependence, including the accessibility of cessation services.
Angela Tripp, Tenecia Smith
doaj   +1 more source

Current practices and perceived barriers to tobacco treatment delivery among healthcare professionals from 15 European countries. The EPACTT Plus project

Tobacco Prevention and Cessation, 2020
Introduction The latest evidence-based Guidelines for Treating Tobacco Dependence highlight the significant role of healthcare professionals in supporting smokers interested to quit.
Charis Girvalaki, Enkeleint A. Mechili, Sophia Papadakis, Katerina Nikitara, Andrey Demin, Antigona Trofor, Arben Lila, Arusyak Harutyunyan, Aurela Saliaj, Deska Dimitrievska, Francisco Rodriguez Lozano, George Bakhturidze, Javier Ayesta, Krzysztof Przewoźniak, Maria Sofia Cattaruzza, Marija Zdraveska, Mihaela Lovše, Biljana Kilibarda, Otto Stoyka, Panagiotis Behrakis, Pierre Bizel, Polina Starchenko, Shkumbin Spahija, Cornel Radu-Loghin, Constantine I. Vardavas   +24 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

EUREST PLUS - European Regulatory Science on Tobacco: Policy implementation to reduce lung diseases - Proposal (Horizon2020)

Tobacco Prevention and Cessation, 2016
EUREST-PLUS, a thirteen –partner EU joint proposal, coordinated by ENSP (Coordinator: Constantine Vardavas), aims to monitor and evaluate the impact of the TPD at an EU level. The specific objectives of the proposal are: 1.
Constantine Vardavas
doaj   +1 more source

Reasons to decrease or stop nicotine and tobacco use among adults and association with MPOWER scores in twenty-one middle- and high-income countries, 2019–2020

Tobacco Prevention and Cessation, 2023
Introduction This study examined reasons why people planned to reduce or stop tobacco consumption and their relationship with MPOWER scores, adjusting for sociodemographic, cultural, and economic factors. Methods Data used were Euromonitor International’
Saida Sharapova, Carrie Whitney, Rose Sulentic, Liping Pan, Indu Ahluwalia   +4 more
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source