Results 41 to 50 of about 385,000 (317)

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

The Economic Impact of Smoking and of Reducing Smoking Prevalence: Review of Evidence [PDF]

BACKGROUND: Tobacco smoking is the cause of many preventable diseases and premature deaths in the UK and around the world. It poses enormous health- and non-health-related costs to the affected individuals, employers, and the society at large.
Ekpu, VU, Brown, AK
core   +1 more source

Patterns and related factors of bidi smoking in India

Tobacco Prevention and Cessation, 2020
Introduction Bidis are the most commonly smoked tobacco product in India. Understanding bidi smoking is important to reducing overall tobacco smoking and health-related consequences in India.
Lazarous Mbulo, Krishna M. Palipudi, Tenecia Smith, Shaoman Yin, Vineet G. Munish, Dhirendra N. Sinha, Prakash C. Gupta, Leimapokpam Swasticharan   +7 more
doaj   +1 more source

European Citizens’ Initiative "Call to achieve a tobacco-free environment and the first European Tobacco-Free Generation by 2030"

Tobacco Prevention and Cessation, 2023
Introduction Given the need for the European Union to advance in legislative measures to end the tobacco pandemic definitively and having the END GAME as a clear objective in the short/medium term, the Spanish NGO Nofumadores created, with the invaluable
Raquel Fernández Megina, Cornel Radu-Loghin, Francisco Rodriguez Lozano   +2 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

TOB-G: Tobacco Cessation Guidelines for High risk Populations

Tobacco Prevention and Cessation, 2016
The TOB-G project is funded under the EU 3rd Health Programme which is the main instrument that the Commission uses to implement the EU Health Strategy. The project started in June 2014 and will be completed in September 2017.
Panagiotis Behrakis
doaj   +1 more source

Impact of the ENSP eLearning platform on improving knowledge, attitudes and self-efficacy for treating tobacco dependence: An assessment across 15 European countries

Tobacco Induced Diseases, 2020
Introduction In 2018, the European Network for Smoking Cessation and Prevention (ENSP) released an update to its Tobacco Treatment Guidelines for healthcare professionals, which was the scientific base for the development of an accredited eLearning ...
Charis Girvalaki, Sophia Papadakis, Enkeleint A. Mechili, Katerina Nikitara, Andrey Demin, Antigona C. Trofor, Arben Lila, Arusyak Harutyunyan, Aurela Saliaj, Deska Dimitrievska, Francisco Rodriguez Lozano, George Bakhturidze, Javier Ayesta, Krzysztof Przewoźniak, Maria Sofia Cattaruzza, Marija Zdraveska, Mihaela Lovše, Biljana Kilibarda, Otto Stoyka, Panagiotis Behrakis, Pierre Bizel, Polina Starchenko, Shkumbin Spahija, Cornel Radu-Loghin, Constantine I. Vardavas   +24 more
doaj   +1 more source

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen, Ceren Tozlu, Tina Roostaei, Fatoumata Diallo, Kaho Onomichi, Jiyeon Son, Zongqi Xia, Philip L. De Jager   +7 more
wiley   +1 more source

Location‐Specific Hematoma Volume Predicts Early Neurological Deterioration in Supratentorial ICH

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Early neurological deterioration (END) adversely affects outcomes in patients with intracerebral hemorrhage (ICH). This study aimed to determine the location‐specific hematoma volumes for END in supratentorial ICH patients. Methods We retrospectively analyzed supratentorial ICH patients presenting from two prospective cohorts.
Zuoqiao Li, Guilin Meng, Zijie Wang, Xiao Hu, Jing Cheng, Chu Chen, Tiannan Yang, Jiaxin Luo, Zizhen Meng, Xueyun Liu, Qi Li   +10 more
wiley   +1 more source