Results 61 to 70 of about 1,347,621 (102)

Cyclic Mechanical Stretch Induced Smooth Muscle Cell Changes in Cerebral Aneurysm Progress by Reducing Collagen Type IV and Collagen Type VI Levels

Cellular Physiology and Biochemistry, 2018
Background/Aims: Cerebral aneurysm growth is characterized by continuous structural weakness of local smooth muscle cells, though the mechanism is unclear.
Peixi Liu, Yaying Song, Yingjie Zhou, Yingjun Liu, Tianming Qiu, Qingzhu An, Jianping Song, Peiliang Li, Yuan Shi, Sichen Li, Kai Quan, Guo-Yuan Yang, Wei Zhu   +12 more
doaj   +1 more source

CREB depletion in smooth muscle cells promotes medial thickening, adventitial fibrosis and elicits pulmonary hypertension

Pulmonary Circulation, 2020
Levels of the cAMP-responsive transcription factor, CREB, are reduced in medial smooth muscle cells in remodeled pulmonary arteries from hypertensive calves and rats with chronic hypoxia-induced pulmonary hypertension.
Chrystelle V. Garat, Susan M. Majka, Timothy M. Sullivan, Joseph T. Crossno, Jane E.B. Reusch, Dwight J. Klemm   +5 more
doaj   +1 more source

Implanted Mouse Bone Marrow-Derived Cells Reconstruct Layered Smooth Muscle Structures in Injured Urinary Bladders

Cell Transplantation, 2008
This study is a preliminary investigation to determine if bone marrow-derived cells, when implanted into freeze-injured urinary bladders, differentiate into smooth muscle cells and reconstruct smooth muscle layers.
Tetsuya Imamura, Yoshiaki Kinebuchi, Osamu Ishizuka, Satoshi Seki, Yasuhiko Igawa, Osamu Nishizawa   +5 more
doaj   +1 more source

Airway Remodeling and Airway Smooth Muscle in Asthma

Allergology International, 2006
Airway remodeling in asthma has been recognized as structural changes of airways such as smooth muscle hypertrophy (an increase in size of airway smooth muscle cells) and hyperplasia (an increase in the number of airway smooth muscle cells), thickening ...
Mitsuru Munakata
doaj   +1 more source

Signal Transduction and Smooth Muscle

, 2019
All hollow organs, such as blood vessels, the gastrointestinal tract, airways, male and female reproductive systems, and the urinary bladder are primarily composed of smooth muscle. Such organs regulate flow, propulsion and mixing of luminal contents and

core  

Rare giant perianal smooth muscle tumor: A case report

Journal of International Medical Research
Smooth muscle tumors are benign tumors originating from smooth muscle tissues, mostly occurring in the uterus and digestive tract; however, smooth muscle tumors occurring in the perianal sphincter are very rare.
Yuanchao Guo, Yi Song, Xiaona Li, Houhua Liu, Tao Wei, Maowei Yang, Chaonan Zhang, Xingang Li   +7 more
doaj   +1 more source

Senescence as a Driver of Smooth Muscle Cell Plasticity and Atherosclerosis: Mechanisms and Therapeutic Opportunities

Cells
Cell senescence is increasingly recognized as a key driver of atherosclerosis progression. Senescent smooth muscle cells (SMCs) lose their proliferative capacity and adopt a pro-inflammatory profile, contributing to impaired vessel repair and weakening ...
Lisa Steegen, Mandy O. J. Grootaert
doaj   +1 more source

Study of calcium sparks in skeletal and smooth muscle cells in normal and pathological conditions [PDF]

, 2016
mTOR signaling influence a wide range of cellular process including protein synthesis (Iadevaia et al., 2012; Ma and Blenis, 2009; Thoreen et al., 2012), lipids synthesis (Lamming and Sabatini, 2013), transcription (Dibble and Manning, 2013; Vazquez ...
López, Rubén
core   +1 more source

Three-dimensional-mapping of smooth muscle morphogenesis in the vertebrate gastrointestinal tract

Scientific Reports
Gastrointestinal (GI) motility depends on smooth muscle contractions to propel contents through the digestive tract. GI muscle is organized into two perpendicular layers: the inner circular smooth muscle (CSM) and the outer longitudinal smooth muscle ...
Salomé Ruiz Demoulin, Amandine Falco, Norbert Chauvet, Pascal de Santa Barbara, Sandrine Faure   +4 more
doaj   +1 more source

CNP-pGC-cGMP-PDE3-cAMP Signal Pathway Upregulated in Gastric Smooth Muscle of Diabetic Rats

Gastroenterology Research and Practice, 2015
Our previous studies have shown that CNP-NPR-B/pGC-cGMP is upregulated in the diabetic rats. The present study was designed to determine whether the upregulation of CNP-NPR-B/pGC-cGMP signal pathway affects cGMP-PDE3-cAMP signal pathway in diabetic ...
Ying-Lan Cai, Mo-Han Zhang, Xu Huang, Jing-Zhi Jiang, Li-Hua Piao, Zheng Jin, Wen-Xie Xu   +6 more
doaj   +1 more source