Results 131 to 140 of about 6,895,201 (344)

PDGF-mediated autophagy regulates vascular smooth muscle cell phenotype and resistance to oxidative stress

Biochemical Journal, 2013
SYNOPSIS Vascular injury and chronic arterial diseases result in exposure of vascular smooth muscle cells (VSMCs) to increased concentrations of growth factors.
Joshua K. Salabei, Timothy D. Cummins, Mahavir Singh, Steven P. Jones, A. Bhatnagar, B. Hill   +5 more
semanticscholar   +1 more source

Cellular and molecular components of the atherosclerotic process: Primary colture and characterization of human vascular smooth muscle cells from carotid artery [PDF]

, 2009
Introduction The last years were characterized by several studies proceeding to understand SMC heterogeneity. Animal models of rat or rabbit IT after endothelial lesion are presently the most studied models for atherosclerotic plaque formation and ...
Gagliano, Teresa
core  

PLL‐g‐HPA Hydrogel Microneedles Loaded With Rhoifolin Target Macrophages to Alleviate Fibroblast Senescence for Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
Diabetic wound healing is hindered by a pathological crosstalk wherein elevated IL‐11 induces M1 macrophage polarization, leading to IL‐1β/IL‐6 release and subsequent fibroblast senescence via RAS/p38MAPK/p53/E2F1 signaling. Here, we develop a Gel@M‐Rho microneedle patch that delivers rhoifolin‐loaded, macrophage membrane‐coated nanoparticles to target
Jiewen Liao, Lin Gan, Li Lu, Lizhi Ouyang, Yuan Xiong, Fawwaz Al‐Smadi, Guandong Dai, Mohammad‐Ali Shahbazi, Bobin Mi, Mengfei Liu, Guohui Liu   +10 more
wiley   +1 more source

Lack of α8 integrin leads to morphological changes in renal mesangial cells, but not in vascular smooth muscle cells

BMC Cell Biology, 2010
Background Extracellular matrix receptors of the integrin family are known to regulate cell adhesion, shape and functions. The α8 integrin chain is expressed in glomerular mesangial cells and in vascular smooth muscle cells.
Hilgers Karl F, Goppelt-Struebe Margarete, Özcan Zehra, Zürn Christina, Fahlbusch Fabian, Jahn Angelika, Volkert Gudrun, Marek Ines, Rascher Wolfgang, Hartner Andrea   +9 more
doaj   +1 more source

The Role of IgE-Receptors in IgE-Dependent Airway Smooth Muscle Cell Remodelling

PLoS ONE, 2013
Background In allergic asthma, IgE increases airway remodelling but the mechanism is incompletely understood. Airway remodelling consists of two independent events increased cell numbers and enhanced extracellular matrix deposition, and the mechanism by ...
M. Roth, Jun Zhong, C. Zumkeller, C. S’ng, S. Goulet, M. Tamm   +5 more
semanticscholar   +1 more source

M2 signaling in smooth muscle cells

Life Sciences, 1999
M2 receptor stimulation results in the gating of nonselective cation channels in several smooth muscle cell types. However the requirement for current activation includes a rise in cytosolic calcium mediated by M3 receptor induced calcium release. This complex signaling system confers substantial complexity on the interpretation of pharmacological ...
M I, Kotlikoff, P, Dhulipala, Y X, Wang
openaire   +2 more sources

Soft Skins With Reversible Thickness Morphing: Materials, Mechanisms, and Applications

Advanced Materials, EarlyView.
Evolution of electronic skin (e‐skin) technologies toward adaptive, multifunctional soft skins. Phase I highlights early rigid and discrete sensory interfaces. Phase II shows the transition toward flexible, stretchable, and large‐area e‐skin. Phase III captures the emergence of computational e‐skin.
Oliver Ozioko, Chiamaka Akah, Ravinder Dahiya   +2 more
wiley   +1 more source

Regulation of Pulmonary Vascular Smooth Muscle Contractility in Pulmonary Arterial Hypertension: Implications for Therapy

Frontiers in Physiology, 2017
There are two primary components that produce pulmonary arterial hypertension (PAH); aberrant structural changes (smooth muscle cell proliferation, smooth muscle cell hypertrophy, and the deposition of matrix proteins within the media of pulmonary ...
Melissa A. Lyle, Jonathan P. Davis, Frank V. Brozovich   +2 more
doaj   +1 more source

Concerted upregulation of CLP36 and smooth muscle actin protein expression in human endometrium during decidualization [PDF]

, 2005
The human endometrium prepares for implantation of the blastocyst by reorganization of its whole cellular network. Endometrial stroma cells change their phenotype starting around the 23rd day of the menstrual cycle.
Neumaier-Wagner, Peruka, Huppertz, Berthold, Goyal, Pankaj, Rath, Werner, Miehe, Ulrich, Kadyrov, Mamed, Alfer, Joachim, Miehe, U;Neumaier-Wagner, P;Kadyrov, M;Goyal, P;Alfer, J;Rath, W;Huppertz, B   +7 more
core   +1 more source

Metal–Organic Framework‐Preserved Thermostable Microneedle Patch for Minimally Invasive Detection and Monitoring of Kidney Dysfunction

Advanced Materials, EarlyView.
By growing a conformal ZIF‐8 protective layer directly on antibody‐functionalized microneedles, this work converts a fragile biosensing interface into a thermostable diagnostic platform. The MOF@MN patch enables minimally invasive NGAL detection from dermal ISF while supporting cold‐chain‐independent storage and transport for decentralized kidney ...
Yixuan Wang, Ying Liu, Avishek Debnath, Chuang Li, Zheyu Wang, Gayathri Kondepati, Saketh Balmoori, Jeremiah J. Morrissey, Ying Maggie Chen, Limei Tian, Srikanth Singamaneni   +10 more
wiley   +1 more source