Results 211 to 220 of about 6,895,201 (344)

FOXC1 Controls Smooth Muscle Cell Differentiation and Plasticity in Vascular Disease. [PDF]

JACC Basic Transl Sci
Rykaczewska U, Suur BE, Narayanan S, Sundman S, Auguste G, Zhao Q, Zhang X, Prasad I, Hedman Å, Lengquist M, Kronqvist M, Swärd K, Razuvaev A, Mälarstig A, Eriksson P, Miller C, Quertermous T, Hedin U, Matic L.   +18 more
europepmc   +1 more source

Single‐Cell and Spatial Transcriptomics Unveil Key Regulators Governing Cell Differentiation for Schistosoma japonicum Sexual Development

Advanced Science, EarlyView.
Using single‐cell and spatial transcriptomics, we identified key regulators that govern cell differentiation involved in parasite development and egg laying in Schistosoma japonicum. This comprehensive study establishes a foundational resource for understanding schistosome biology, deciphers the regulatory programs underlying cell differentiation and ...
Zhigang Lu, Xiaoxu Wang, Shun Li, Xuxin Li, Pengfei Du, Yameng Zheng, Lu Liu, Yanyan Zhang, Omri Wurtzel, Guofeng Cheng   +9 more
wiley   +1 more source

Neuro-Mechanical Regulation of Vascular Smooth Muscle Cell Behaviour Under Ageing-Associated Substrate Stiffness. [PDF]

Curr Issues Mol Biol
Hou Y, Singal S, Swiatlowska P, Sanchez-Alonso JL.   +3 more
europepmc   +1 more source

The effects of Danirixin, as a CXCR2 antagonist, on smooth muscle function

This research project was conducted in the frame of identifying the possibility of Danirixin use as a future treatment for ileus by proving the direct effect of danirixin on smooth muscle cell function through its signalling as a CXCR2 antagonist and ...
Mesrati, Farah
core  

A Hydrogen Sulfide–Releasing Dynamic Hydrogel Modulates Coordinated Neurovascular, Immune, and Angiogenic Responses for Scar‐Suppressed Diabetic Wound Repair

Advanced Science, EarlyView.
ROS‐Responsive H2S Hydrogel (HAPPF) Coordinated Regeneration for High‐Quality Diabetic Wound Repair.A self‐regulating dynamic hydrogel is developed to deliver a fluorogenic H2S donor in response to excessive ROS. Released H2S acts as a master regulator to resolve chronic inflammation (M2 polarization), restore VEGF‐driven angiogenesis, and rebalance ...
Xuyang Ning, Ziqiang Zhou, Bangming Li, Hong Lu, Haoyang Wen, Zhoulong Huang, Gang Li, Ping Hu   +7 more
wiley   +1 more source

Knockdown of DVL2 inhibits vascular smooth muscle cell proliferation and migration. [PDF]

Sci Rep
Li L, Yao Y, Wang Y, Dong J, Zhang P.
europepmc   +1 more source

MAM‐Localized MANF Counteracts Microinflammatory Stress to Attenuate Mitochondrial Dysfunction and Cataractogenesis in High Myopia

Advanced Science, EarlyView.
Chronic microinflammation in high myopia suppresses MANF in lens epithelial cells. MANF normally resides within MAMs and promotes ubiquitin‐mediated degradation of the ER Ca2+ pump SERCA2. MANF loss causes pathological SERCA2 accumulation, MAM hyperassembly, and disrupted ER‐to‐mitochondria Ca2+ transfer, leading to mitochondrial failure, oxidative ...
Xin Liu, Hao Li, Ching Kang, Dongling Guo, Shuyu Liu, Jiaqi Meng, Zhiqian Huang, Yu Du, Xiangjia Zhu   +8 more
wiley   +1 more source

Smooth muscle cell spheroids as 3D model of phenotypic plasticity and matrix deposition revealed by 2D-3D proteomics. [PDF]

Sci Rep
Hesse J, Resch U, Görtz L, Lang S, Batool R, Saradar S, Schoof P, Gehlweiler K, Zouikova D, Jashnieh P, Fernandes Velosa R, Hotzel-Hacker N, Suzuki F, Bayraktar S, Cappallo M, Schmidt V, Ebbert L, Bülow MH, Kucharowski N, Laakkonen EK, Krüger M, Sengle G, Chadt A, Lichtenberg A, Aubin H, Weber E.   +25 more
europepmc   +1 more source

Close relation of arterial ICC-like cells to the contractile phenotype of vascular smooth muscle cell [PDF]

, 2007
Gordienko, DV, Povstyan, O.V., Povstyan, OV, Oleksandr V. Povstyan, Gordienko, D.V., Vladimír Pucovský, Ray F. Moss, Bolton, T.B., Dmitri V. Gordienko, Bolton, TB, Moss, R.F., Harhun, M.I., Maksym I. Harhun, Thomas B. Bolton, Pucovský, V, Harhun, MI, Pucovsky, Vladimir, Moss, RF   +17 more
core   +1 more source

Harnessing Large‐Scale Multi‐Omics Data for Risk Prediction and Deep Phenotyping of Valvular Heart Diseases in the General Population

Advanced Science, EarlyView.
Large‐scale UK Biobank analyses identify clinical and proteomic signatures for early prediction of valvular heart disease and its subtypes. Proteins add predictive value for VHD, AVS, and MVR, with outcome‐specific compact panels showing translational potential. Multi‐layer evidence highlights matrix remodeling, protease regulation, immune inflammation,
Zhihao Jiang, Yang Liu, Mingyu Song, Ning Chen, Canqing Yu, Jun Lv, Eric Yuk Fai Wan, Lu Qi, Liming Li, Dianjianyi Sun, Bang Zheng   +10 more
wiley   +1 more source