Results 41 to 50 of about 249,477 (266)
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Approximation of Bivariate Functions via Smooth Extensions
For a smooth bivariate function defined on a general domain with arbitrary shape, it is difficult to do Fourier approximation or wavelet approximation. In order to solve these problems, in this paper, we give an extension of the bivariate function on a ...
Zhihua Zhang
doaj +1 more source
Rotundity and smoothness in conjugate spaces [PDF]
It is shown that the James space J J admits an equivalent norm such that its third conjugate space is rotund.
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Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Parametric general variational-like inequality problem in uniformly smooth Banach space
Using the concept of - -proximal mapping, we study the existence and sensitivity analysis of solution of a parametric general variational-like inequality problem in uniformly smooth Banach space.
Kazmi KR, Khan FA
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ON TWO-SIDED UNIDIRECTIONAL MEAN VALUE INEQUALITY IN A FRÉCHET SMOOTH SPACE
The paper is devoted to a new unidirectional mean value inequality for the Fréchet subdifferential of a continuous function. This mean value inequality finds an intermediate point and localizes its value both from above and from below; for this reason ...
Dmitry V. Khlopin
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BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Orthogonality in smooth countably normed spaces
We generalize the concepts of normalized duality mapping, J-orthogonality and Birkhoff orthogonality from normed spaces to smooth countably normed spaces.
Sarah Tawfeek +2 more
doaj +1 more source
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Ordinary Smooth Topological Spaces
In this paper, we introduce the concept of ordinary smooth topology on a set X by considering the gradation of openness of ordinary subsets of X. And we obtain the result [Corollary 2.13] : An ordinary smooth topology is fully determined its decomposition in classical topologies. Also we introduce the notion of ordinary smooth [resp.
Pyung-Ki Lim, Byeong-Guk Ryoo, Kul Hur
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