Results 71 to 80 of about 461,035 (286)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Adaptive Beamforming Based on Compressed Sensing with Smoothed l0 Norm

open access: yesInternational Journal of Antennas and Propagation, 2015
An adaptive beamforming based on compressed sensing with smoothed l0 norm for large-scale sparse receiving array is proposed in this paper. Because of the spatial sparsity of the arriving signal, compressed sensing is applied to sample received signals ...
Yubing Han, Jian Wang
doaj   +1 more source

The relationship between hemoglobin and triglycerides in moyamoya disease: A cross-sectional study

open access: yesFrontiers in Neurology, 2022
Hemoglobin (Hb) and lipid metabolism are critical in the pathophysiology of moyamoya disease (MMD), and Hb and triglycerides (TGs) both play roles in the development of cerebrovascular illness.
Yu Su   +7 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Smoothed analysis of \(\kappa(A)\)

open access: yesJ. Complex., 2004
For a real \(m\) by \(m\) random matrix \(A\) with independent Gaussian entries for the common variance \(\sigma^2\) and the matrix \(M\) of expected values of \(A\), the author proves that the probability of the condition number \(\kappa_2(A)=\| A\| _2 \cdot \| A^{-1}\| _2\) of \(A\) exceeding \(m \cdot x\) for any positive \(x\) is bounded by ...
openaire   +3 more sources

STATISTICAL METHODS OF ANALYSIS OF FINANCIAL INDICATORS NEEDED TO MODEL VALUATIONS

open access: yesСтатистика и экономика, 2016
The article presents the methods of analysis and interpretation of financial performance required to create a comprehensive and universal model of valuation.
Ivan E. Akulin
doaj   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Smoothed Analysis of Binary Search Trees

open access: yesTheoretical Computer Science, 2005
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Manthey, Bodo, Reischuk, Rüdiger
openaire   +1 more source

Addendum to "On the consistency of MPS"

open access: yes, 2013
The analogies between the Moving Particle Semi-implicit method (MPS) and Incompressible Smoothed Particle Hydrodynamics method (ISPH) are established in this note, as an extension of the MPS consistency analysis conducted in "Souto-Iglesias et al ...
Cercos-Pita, Jose L.   +3 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

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