Results 51 to 60 of about 461,035 (286)

Smoothed Weighted Quantile Regression for Censored Data in Survival Analysis

open access: yesAxioms
In this study, we propose a smoothed weighted quantile regression (SWQR), which combines convolution smoothing with a weighted framework to address the limitations.
Kaida Cai   +3 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Analysis of uncertain data: Smoothing of histograms [PDF]

open access: yes2009 IEEE International Conference on Systems, Man and Cybernetics, 2009
We consider the problem of converting a set of numeric data points into a smoothed approximation of the underlying probability distribution. We describe a representation of distributions by histograms with variable-width bars, and give a greedy smoothing algorithm based on this representation.
Eugene Fink   +2 more
openaire   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Measurement-induced decoherence and Gaussian smoothing of the Wigner distribution function

open access: yes, 2003
We study the problem of measurement-induced decoherence using the phase-space approach employing the Gaussian-smoothed Wigner distribution function.
Ali   +44 more
core   +2 more sources

Smoothed Analysis for Graph Isomorphism

open access: yesProceedings of the 57th Annual ACM Symposium on Theory of Computing
There is no known polynomial-time algorithm for graph isomorphism testing, but elementary combinatorial "refinement" algorithms seem to be very efficient in practice. Some philosophical justification is provided by a classical theorem of Babai, Erdős and Selkow: an extremely simple polynomial-time combinatorial algorithm (variously known as "naïve ...
Michael Anastos   +2 more
openaire   +2 more sources

Smoothed Analysis of Order Types

open access: yesCoRR, 2019
15 pages, 6 figures, long introduction and short ...
Hoog, Ivor van der   +2 more
openaire   +4 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Spatial association between the incidence rate of COVID-19 and poverty in the São Paulo municipality, Brazil

open access: yesGeospatial Health, 2020
In this article, we investigated the spatial dependence of the incidence rate by COVID-19 in the São Paulo municipality, Brazil, including the association between the spatially smoothed incidence rate (INC_EBS) and the social determinants of poverty, the
Marcos César Ferreira
doaj   +1 more source

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