Results 41 to 50 of about 168,055 (268)
Tracking and Estimation of Multiple Cross-Over Targets in Clutter
Sensors, 2019 Tracking problems, including unknown number of targets, target trajectories behaviour and uncertain motion of targets in the surveillance region, are challenging issues.
Sufyan Ali Memon +2 more
doaj +1 more source
Comparison of Parametric and Nonparametric Forecasting Methods for Daily COVID-19 Cases in Malaysia
JOIV: International Journal on Informatics Visualization, 2023 Numerous research studies are currently examining various measures to control the transmission of COVID-19. One essential task in this regard is predicting or forecasting the number of infected individuals.
I Made Artha Agastya, Afrig Aminuddin
doaj +1 more source
Journal of Knot Theory and Its Ramifications, 2012 We construct two knot invariants. The first knot invariant is a matrix constructed using linking numbers. This matrix can be represented as a two variable polynomial. The second is an invariant of flat knots and is a formal sum of flat knots obtained by smoothing pairs of crossings. This invariant can be used in conjunction with other flat invariants,
openaire +3 more sources
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
IEEE Access, 2021 Nowadays, the Direction of Arrival (DoA) estimation problem attracts much attention because of emerging use cases for wireless networks. DoA is beneficial for Reconfigurable Intelligent Surfaces, indoor localization, and various navigation and sensing ...
Vladislav Molodtsov +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Stochastic Aspects of Proportional Vitalities Model
Mathematics, 2020 In this paper, a family of models requiring proportional mean life vitalities is considered. The problem of estimation of the parameter(s) of the model is studied in two cases of known and unknown baselines along with some simulation studies to detect ...
Mansour Shrahili +3 more
doaj +1 more source