Results 61 to 70 of about 160,558 (267)
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
A smooth horizon without a smooth horizon
Journal of High Energy PhysicsAbstract Recent observations on type III algebras in AdS/CFT raise the possibility that smoothness of the black hole horizon is an emergent feature of the large-N limit. In this paper, we present a bulk model for the finite-N mechanism underlying this transition.
Burman, V, Das, S, Krishnan, C
openaire +5 more sources
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
FEBS Open Bio, EarlyView.RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
Bayesian Functional Data Analysis Using WinBUGS
Journal of Statistical Software, 2010 We provide user friendly software for Bayesian analysis of functional data models using WinBUGS 1.4. The excellent properties of Bayesian analysis in this context are due to: (1) dimensionality reduction, which leads to low dimensional projection bases; (
Ciprian M. Crainiceanu +1 more
doaj
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Contexte théorique de la notion de discontinuité géographique
Cybergeo, 2002 Likeness and proximity are studied in the particular context of geographical discontinuity, in both clustered (bounded) and continuous spaces. First, likeness and proximity are linked: likeness could be spatial and/or social; moreover, social structures ...
J.C. François
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FEBS Open Bio, EarlyView.Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas +6 more
wiley +1 more source
Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley +1 more source
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Aging and Cancer, EarlyView.Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source
, 2006 A smooth orchestrator is a process with several alternative branches, every one defining synchronizations among co-located channels. Smooth orchestrators constitute a basic mechanism that may express standard workflow patterns in Web services as well as common synchronization constructs in programming languages.
LANEVE, COSIMO, Padovani L.
openaire +3 more sources