Results 61 to 70 of about 1,946,431 (327)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Smoothing migration intensities with P-TOPALS

open access: yesDemographic Research, 2020
Background: Age-specific migration intensities often display irregularities that need to be removed by graduation, but two current methods for doing so, parametric model migration schedules and non-parametric kernel regression, have their limitations ...
Sigurd Dyrting
doaj   +1 more source

A Probabilistic Perspective on Gaussian Filtering and Smoothing

open access: yes, 2010
We present a general probabilistic perspective on Gaussian filtering and smoothing. This allows us to show that common approaches to Gaussian filtering/smoothing can be distinguished solely by their methods of computing/approximating the means and ...
Deisenroth, MP, Ohlsson, H
core   +1 more source

Smooth and F--smooth systems

open access: yes, 2020
We review the geometric theory of \emp{smooth systems of smooth maps}, of \emp{smooth systems of smooth sections} of a smooth double fibred manifold and of \emp{smooth systems of smooth connections} of a smooth fibred manifold. Moreover, after reviewing the concept of \emp{F-smooth space} due to A.
Janyška, Josef, Modugno, Marco
openaire   +2 more sources

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

State-Space Models on the Stiefel Manifold with a New Approach to Nonlinear Filtering

open access: yesEconometrics, 2018
We develop novel multivariate state-space models wherein the latent states evolve on the Stiefel manifold and follow a conditional matrix Langevin distribution.
Yukai Yang, Luc Bauwens
doaj   +1 more source

Managerial Ability and Income Smoothing

open access: yesAccounting Review, 2019
In this study, we investigate whether managerial ability is related to income smoothing and, if so, whether smoothing associated with managerial ability improves the informativeness of earnings and stock prices about future performance.
Bok Baik, Sunhwa Choi, D. Farber
semanticscholar   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Image Filtering With Generic Geometric Prior

open access: yesIEEE Access, 2018
This paper first presents a generic geometric prior for the image processing problems. The proposed term allows each individual pixel to automatically choose its own geometric prior.
Yuanhao Gong   +3 more
doaj   +1 more source

iSAM2: Incremental smoothing and mapping using the Bayes tree

open access: yesInt. J. Robotics Res., 2012
We present a novel data structure, the Bayes tree, that provides an algorithmic foundation enabling a better understanding of existing graphical model inference algorithms and their connection to sparse matrix factorization methods.
M. Kaess   +5 more
semanticscholar   +1 more source

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