Results 61 to 70 of about 159,943 (267)
Improved Confidence Intervals for Expectiles
Expectiles were introduced to statistics around 40 years ago, but have recently gained renewed interest due to their relevance in financial risk management.
Spiridon Penev, Yoshihiko Maesono
doaj +1 more source
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
On Smoothing and the Bootstrap
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Hall, Peter +2 more
openaire +2 more sources
SATELLITE ALTIMETER DATA FILTERING AND SMOOTHING IN THE COURSE OF GROUND-BASED RETRACKING
Introduction. Satellite radar altimeter is an essential part of the Earth remote sensing space missions. Satellite altimeter on-board delay-lock loop, by a widely shared concept, is operationally just a tool of a reliable retaining of received echo ...
D. S. Borovitsky +3 more
doaj +1 more source
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
A smooth horizon without a smooth horizon
Abstract Recent observations on type III algebras in AdS/CFT raise the possibility that smoothness of the black hole horizon is an emergent feature of the large-N limit. In this paper, we present a bulk model for the finite-N mechanism underlying this transition.
Burman, V, Das, S, Krishnan, C
openaire +5 more sources
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source

