Results 241 to 250 of about 386,050 (293)

Dual‐Peptide Nanoplatform: Mesoporous Silica Nanoparticles Functionalized With a Cell‐Penetrating Peptide and Loaded With Rationally Designed Antimicrobial Peptides for Tuberculosis Therapy

Advanced Healthcare Materials, EarlyView.
Machine learning–guided engineering of a plectasin‐derived peptide yields DC05, a potent antimycobacterial candidate. Encapsulation into tuftsin‐functionalized mesoporous silica nanoparticles enhances intracellular delivery, stability, and activity against Mycobacterium tuberculosis while maintaining low cytotoxicity and minimal hemolysis. The combined
Christian S. Carnero Canales, Cesar Augusto Roque‐Borda, Ana Carolina Cerqueira Negri, Oswaldo Ramirez Delgado, Letícia Oliveira Catarin Nunes, Flávia Aparecida Resende, Hernane Barud, Norival Alves Santos‐Filho, Saulo Santesso Garrido, Karen Cristina Oliveira, Alexandra Ivo de Medeiros, Rafael Miguel Sábio, Fernando Rogério Pavan   +12 more
wiley   +1 more source

Simulation-based assessment of a Bayesian M-spline survival model with flexible baseline hazard and time-dependent effects. [PDF]

BMC Med Res Methodol
Timmins IR, Torabi F, Jackson CH, Lambert PC, Sweeting MJ.   +4 more
europepmc   +1 more source

Optoelectrical Devices for Neural Interfacing: Engineering Integration, Stability, and Multimodal Sensing

Advanced Healthcare Materials, EarlyView.
Implantable optoelectrical devices are an effective resource for the modulation and monitoring of neural activity with high spatiotemporal resolution. This review discusses current challenges faced by these devices and outlines future perspectives for the development of next‐generation neural interfaces targeting chronic, multisite, and multimodal ...
Stella Aslanoglou, Barbara Spagnolo, Antonio Balena, Massimo De Vittorio, Ferruccio Pisanello   +4 more
wiley   +1 more source

A Modular Bioinstructive Platform Reveals Mechanistic Insights into Additive‐Free, Topography‐Driven Osteogenesis

Advanced Healthcare Materials, EarlyView.
Engineered microparticle topographies direct human mesenchymal stem cell osteogenesis without biochemical additives. This osteogenic commitment is driven by canonical Hedgehog signaling and followed by temporal IGF‐II engagement. Two‐photon polymerization demonstrates spatial control, enabling the engineering of topographical gradients that pattern ...
Fatmah I. Ghuloum, Leo A. H. Zeef, Lee A. Stevens, Marco A. N. Domingos, Susan J. Kimber, Mahetab H. Amer   +5 more
wiley   +1 more source

Fast Bayesian Functional Principal Components Analysis. [PDF]

J Comput Graph Stat
Sartini J, Zhou X, Selvin E, Zeger S, Crainiceanu CM.   +4 more
europepmc   +1 more source

Segmentation for Learning Adsorption Patterns and Residence-Time Kinetics on Amorphous Surfaces. [PDF]

J Chem Inf Model
Turchi M, Lunati I.
europepmc   +1 more source

Automated Facial Pain Assessment Using Dual-Attention CNN with Clinically Calibrated High-Reliability and Reproducibility Framework. [PDF]

Biomimetics (Basel)
Sankoh AP, Raza A, Parwez K, Shishah W, Alharbi A, Javed M, Bilal M.   +6 more
europepmc   +1 more source

Robust uncertainty quantification in popular estimators of the instantaneous reproduction number. [PDF]

Am J Epidemiol
Steyn N, Parag KV.
europepmc   +1 more source

Research on AUV Underwater Localization Method Based on an n-Shaped Array. [PDF]

Sensors (Basel)
Han C, Gao M, Shen T, Guo C.
europepmc   +1 more source