Results 61 to 70 of about 1,663,953 (297)

Using fluorescence fluctuation spectroscopy to quantify molecular dynamics within cells

open access: yesFEBS Open Bio, EarlyView.
Microscopy techniques like fluorescence correlation spectroscopy (FCS) and number and brightness analysis (N&B) allow to quantify concentrations, diffusion rates, and oligomerization of fluorescently labeled molecules in the living cell. In this protocol the principles of how to set up these types of experiments are described including calibration ...
Mark A. Hink
wiley   +1 more source

Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani   +10 more
wiley   +1 more source

The Jacobian Consistency of a One-Parametric Class of Smoothing Functions for SOCCP

open access: yesAbstract and Applied Analysis, 2013
Second-order cone (SOC) complementarity functions and their smoothing functions have been much studied in the solution of second-order cone complementarity problems (SOCCP).
Xiaoni Chi, Zhongping Wan, Zijun Hao
doaj   +1 more source

Spline Smoothing with an Estimated Order Parameter

open access: yesThe Annals of Statistics, 1993
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +3 more sources

Spatial and Volumetric Characteristics of Glioblastoma: Associations With Clinical Presentation and Survival

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We aim to comprehensively analyze how regional tumor and edema characteristics are associated with clinical presentations and survival outcomes in a large cohort of glioblastoma patients. Methods Patients with IDH‐wildtype glioblastoma who received brain MRI from 2010 to 2023 were included.
Daniel J. Zhou   +16 more
wiley   +1 more source

Robust generalized cross-validation for choosing the regularization parameter [PDF]

open access: yes, 2006
Let fλ be the regularized solution for the problem of estimating a function or vector f0 from noisy data yi ≤ Lif0 + εi, i ≤ 1, ..., n, where Li are linear functionals.
Lukas, M.A.
core  

Evaluation of threshold selection methods for adaptive kernel density estimation in disease mapping

open access: yesInternational Journal of Health Geographics, 2018
Background Maps of disease rates produced without careful consideration of the underlying population distribution may be unreliable due to the well-known small numbers problem.
Warangkana Ruckthongsook   +3 more
doaj   +1 more source

Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon   +5 more
wiley   +1 more source

Comparing parameter choice methods for regularization of ill-posed problems [PDF]

open access: yes, 2011
In the literature on regularization, many different parameter choice methods have been proposed in both deterministic and stochastic settings. However, based on the available information, it is not always easy to know how well a particular method will ...
Bauer, F., Lukas, M.A.
core  

Sex‐Stratified Association of Regional Dopamine Transporter Binding With Disease Progression in Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe   +7 more
wiley   +1 more source

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