Results 41 to 50 of about 448,585 (316)

Efficient algorithms for robust generalized cross-validation spline smoothing

, 2010
Generalized cross-validation (GCV) is a widely used parameter selection criterion for spline smoothing, but it can give poor results if the sample size n is not sufficiently large.
Anderssen, R.S., de Hoog, Frank R., Anderssen, Robert S., de Hoog, F.R., Lukas, M.A., Lukas, Mark A.   +5 more
core   +1 more source

Ecient Parameter Estimation and Control Based on a Modified LOS Guidance System of an Underwater Vehicle

Revista Iberoamericana de Automática e Informática Industrial RIAI, 2017
In this work, a methodology is proposed for the improvement of the parameter estimation effciency of a non-linear manoeuvring model of a torpedo shaped unmanned underwater vehicle.
Elías Revestido Herrero, Francisco J. Velasco, Luis M. Vega, Francisco J. Lastra   +3 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

A hybrid simple exponential smoothing-barnacles mating optimization approach for parameter estimation: Enhancing COVID-19 forecasting in Malaysia

MethodsX
Single or simple exponential smoothing (SES) is a time series forecasting model popular among researchers due to its simplicity and ease of use. SES only requires one smoothing parameter, alpha, to control how quickly the influence of past observations ...
Azlan Abdul Aziz, Zuriani Mustaffa, Suzilah Ismail, Nor Azriani Mohamad Nor, Nurin Qistina Mohamad Fozi   +4 more
doaj   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Computationally Efficient Bootstrap Expressions for Bandwidth Selection in Nonparametric Curve Estimation

Proceedings, 2018
Bootstrap methods are used for bandwidth selection in: (1) nonparametric kernel density estimation with dependent data (smoothed stationary bootstrap and smoothed moving blocks bootstrap), and (2) nonparametric kernel hazard rate estimation (smoothed ...
Inés Barbeito, Ricardo Cao
doaj   +1 more source

HISAPS: High-order smoothing spline with automatic parameter selection and shape constraints

SoftwareX
Obtaining a good functional fit with noisy data is difficult. This is especially true when the derivative of the fitted function is needed, which is often the case in engineering applications. One solution is to use smoothing splines.
Peter H. Broberg, Esben Lindgaard, Asbjørn M. Olesen, Simon M. Jensen, Niklas K.K. Stagsted, Rasmus L. Bjerg, Riccardo Grosselle, Iñigo Urcelay Oca, Brian L.V. Bak   +8 more
doaj   +1 more source

Comparison of total variation with a motion estimation based compressed sensing approach for self-gated cardiac cine MRI in small animal studies. [PDF]

PLoS ONE, 2014
PURPOSE: Compressed sensing (CS) has been widely applied to prospective cardiac cine MRI. The aim of this work is to study the benefits obtained by including motion estimation in the CS framework for small-animal retrospective cardiac cine.
Juan F P J Abascal, Paula Montesinos, Eugenio Marinetto, Javier Pascau, Manuel Desco   +4 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Bandwidth Selection Problem for Nonparametric Regression Model with Right-Censored Data [PDF]

Revista Română de Statistică, 2017
In this paper, the proposed estimator for the unknown nonparametric regression function is a Nadarya-Watson (Nadarya, 1964; Watson, 1964) type kernel estimator. In this estimation procedure, the censored observations are replaced by synthetic data points
Dursun AYDIN, Ersin YILMAZ
doaj