Results 61 to 70 of about 3,817,143 (297)

Robust generalized cross-validation for choosing the regularization parameter [PDF]

open access: yes, 2006
Let fλ be the regularized solution for the problem of estimating a function or vector f0 from noisy data yi ≤ Lif0 + εi, i ≤ 1, ..., n, where Li are linear functionals.
Lukas, M.A.
core  

Baseline Neuroinflammation Stratifies TSPO‐PET Response to Disease‐Modifying Therapy in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate which baseline clinical and imaging characteristics best predict TSPO‐PET‐measurable reduction in glial activation following treatment of multiple sclerosis (MS), to utilize this information for designing more efficient biomarker‐based clinical trials targeting glial activation.
Marlene T. Morch   +5 more
wiley   +1 more source

Multiple smoothing parameters selection in additive regression quantiles

open access: yesStatistical Modelling, 2020
We propose an iterative algorithm to select the smoothing parameters in additive quantile regression, wherein the functional forms of the covariate effects are unspecified and expressed via B-spline bases with difference penalties on the spline coefficients.
Muggeo, Vito M.R.   +4 more
openaire   +3 more sources

Gravity‐Dependent Modulation of Downbeat Nystagmus: Insights From Velocity‐Storage Dysfunction

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Downbeat nystagmus varies with head position, a phenomenon termed gravity‐dependent modulation. We aimed to clarify its mechanism using a velocity‐storage model. Methods In 10 patients with downbeat nystagmus due to cerebellar disorders, we recorded eye movements at different pitch‐ and roll‐axis head positions.
Ji‐Hyung Park   +5 more
wiley   +1 more source

Bandwidth Selection Problem in Nonparametric Functional Regression [PDF]

open access: yesStatistika: Statistics and Economy Journal, 2017
The focus of this paper is the nonparametric regression where the predictor is a functional random variable, and the response is a scalar. Functional kernel regression belongs to popular nonparametric methods used for this purpose. The two key problems
Daniela Kuruczová, Jan Koláček
doaj  

Smoothing internal migration age profiles for comparative research

open access: yesDemographic Research, 2015
Background: Age patterns are a key dimension to compare migration between countries and over time. Comparative metrics can be reliably computed only if data capture the underlying age distribution of migration.
Aude Bernard, Martin Bell
doaj   +1 more source

Smoothing and Differentiation of Kinematic Data Using Functional Data Analysis Approach: An Application of Automatic and Subjective Methods

open access: yesApplied Sciences, 2020
Smoothing is one of the fundamental procedures in functional data analysis (FDA). The smoothing parameter λ influences data smoothness and fitting, which is governed by selecting automatic methods, namely, cross-validation (CV) and generalized ...
Muhammad Athif Mat Zin   +3 more
doaj   +1 more source

Stage‐Dependent β‐Synuclein Links MRI and Cognitive Decline in Alzheimer's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Synaptic degeneration drives cognitive decline in Alzheimer's disease (AD), but synaptic biomarkers are scarce. Brain‐enriched β‐synuclein emerged as a synaptic damage marker. We investigated its diagnostic, prognostic, and structural correlates across the AD continuum.
Ulaş Ay   +15 more
wiley   +1 more source

Resistant Nonparametric Smoothing with S-PLUS [PDF]

open access: yes
In this paper we introduce and illustrate the use of an S-PLUS set of functions to fit M-type smoothing splines with the smoothing parameter chosen by a robust criterion (either a robust version of cross-validation or a robust version of Mallows's Cp ...
Eva Cantoni
core  

Clinical, Histologic, and Serological Predictors of Renal Function Loss in Lupus Nephritis

open access: yesArthritis Care &Research, EarlyView.
Objective Kidney survival is the ultimate goal in lupus nephritis (LN) management, but long‐term predictors remain inadequately studied, requiring long‐term follow‐up. This study aimed to identify baseline and early longitudinal predictors of kidney survival in the Accelerating Medicines Partnership LN longitudinal cohort.
Shangzhu Zhang   +21 more
wiley   +1 more source

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