Results 61 to 70 of about 448,585 (316)

The Impact of Smoothing Techniques on Vegetation Phenology Extraction: A Case Study of Inner Mongolia Grasslands

Agronomy
The selection of data smoothing methods is one of the key steps in extracting land surface phenology parameters from time-series remote sensing data. However, existing studies often use default parameters for denoising the time-series data, neglecting ...
Mengna Liu, Baocheng Wei, Xu Jia
doaj   +1 more source

Semiparametric models and P-splines [PDF]

, 2001
P-splines were introduced by Eilers and Marx (1996). We consider semiparametric models where the smooth part of the model can be described by P-splines. A mixed model representation is also considered.
M., Durbán,, Currie, Iain David, I., Currie,, Durban, M   +3 more
core  

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

Bayesian data assimilation for estimating instantaneous reproduction numbers during epidemics: Applications to COVID-19.

PLoS Computational Biology, 2022
Estimating the changes of epidemiological parameters, such as instantaneous reproduction number, Rt, is important for understanding the transmission dynamics of infectious diseases.
Xian Yang, Shuo Wang, Yuting Xing, Ling Li, Richard Yi Da Xu, Karl J Friston, Yike Guo   +6 more
doaj   +1 more source

Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani, Emmanuel Barbeau, Béatrice Lemesle, Emilie Milongo‐Rigal, Sophie Fernandez, Sandrine Charpentier, Jean‐François Albucher, Nicolas Raposo, Fabrice Bonneville, Patrice Péran, Jérémie Pariente   +10 more
wiley   +1 more source

Smoothing and Differentiation of Kinematic Data Using Functional Data Analysis Approach: An Application of Automatic and Subjective Methods

Applied Sciences, 2020
Smoothing is one of the fundamental procedures in functional data analysis (FDA). The smoothing parameter λ influences data smoothness and fitting, which is governed by selecting automatic methods, namely, cross-validation (CV) and generalized ...
Muhammad Athif Mat Zin, Azmin Sham Rambely, Noratiqah Mohd Ariff, Muhammad Shahimi Ariffin   +3 more
doaj   +1 more source

Image Quality and Quantitative Accuracy of Small Animal PET Images: Role of Physical Effects Correction and Reconstruction Algorithm [PDF]

Egyptian Journal of Nuclear Medicine, 2012
Positron emission tomography (PET) provides important metabolic information about tracer kinetics. Photon attenuation, scattered radiation, spatial resolution limitation and reconstruction algorithm parameters are variables that influence image quality ...
Magdy Khalil
doaj   +1 more source

Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon, Hugues Chabriat, Dominique Hervé, Stéphanie Guey, Sophie Tezenas Du Montcel, Juliette Ortholand   +5 more
wiley   +1 more source