Results 51 to 60 of about 806,737 (291)

New Smoothness Indicator Within an Active Flux Framework

CoRR
In this work, we introduce a new smoothness indicator (SI), which is capable of detecting ``rough'' parts of the solutions computed by active flux (AF) methods for hyperbolic (systems of) conservation laws. The new SI is based on measuring the difference between the two sets of solutions (either cell averages and point values or cell averages on ...
Alina Chertock, Alexander Kurganov, Lorenzo Micalizzi   +2 more
openaire   +3 more sources

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Assembly line balancing in an electronics company using simulation approach

MATEC Web of Conferences, 2018
One of the efforts company did continuously to compete was to reduce waste or anything that is not adding value to products such as waiting activity that cause unbalance of workload between workstations on a production path.
Syahputri Khalida, Leviza Jelly, Sari Sari, Indah Rizkya T, Napitupulu Humala, Anizar Anizar   +5 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Monophonic and Polyphonic Wheezing Classification Based on Constrained Low-Rank Non-Negative Matrix Factorization

Sensors, 2021
The appearance of wheezing sounds is widely considered by physicians as a key indicator to detect early pulmonary disorders or even the severity associated with respiratory diseases, as occurs in the case of asthma and chronic obstructive pulmonary ...
Juan De La Torre Cruz, Francisco Jesús Cañadas Quesada, Nicolás Ruiz Reyes, Sebastián García Galán, Julio José Carabias Orti, Gerardo Peréz Chica   +5 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Local adaptivity to inhomogeneous smoothness. 1. Resolution level [PDF]

, 1994
The problem of nonparametric estimation of functions of inhomogeneous smoothness is considered. The goal is to define the notion of local smoothness of a function ƒ(·), to evaluate the optimal rate of convergence of estimators (depending on this local ...
Lepski, Oleg V., Spokoiny, Vladimir
core   +1 more source

A high-resolution WENO scheme with multiple global smoothness indicators in compressible fluids

Results in Applied Mathematics
A novel fifth-order WENO-Z-type scheme with multiple global smoothness indicators (MGSI-WENO-Z) is proposed for compressible multi-scale flows. Unlike conventional WENO-Z schemes with a single global smoothness indicator, distinct GSIs are assigned to ...
Shujiang Tang, Yuelong Tang
doaj   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source