Results 191 to 200 of about 53,718 (300)

Multi-Omics Mendelian Randomization and Clinical Validation Implicate NLRP6 as a Candidate Autophagy-Related Gene in Systemic Lupus Erythematosus. [PDF]

Genes (Basel)
Nie D, Yin J, Tu W, Huang K, Wan J, Yu Y, Wang B, Chen Y, Lin S, Zeng Z.   +9 more
europepmc   +1 more source

Pharmacological Modulation of Nrf2 Signaling Regulates Oxidative Stress, Inflammation, and Alveolar Bone Loss in Experimental Periodontitis

Journal of Periodontal Research, EarlyView.
Pharmacological activation of Nrf2 attenuated alveolar bone loss and protected periodontal tissues by reducing inflammation and oxidative stress, preserving collagen organization, and favoring bone homeostasis. Reversal of these effects by Nrf2 inhibition further supports Nrf2 signaling as a promising therapeutic target in periodontitis.
Vitória Bonan Costa, Mariely Araújo de Godoi, Angelo Constantino Camilli, Isabela Rinaldi Gomes Nogueira, Veronica Canela Estevam dos Santos, Lucas Nogueira Ramos, Juliana Silva Siqueira, Camila Renata Corrêa Camacho, Morgana Rodrigues Guimarães Stabili   +8 more
wiley   +1 more source

Integrating multi-omics and reverse network toxicology to identify pollutant risks and potential intervention targets in pulmonary arterial hypertension. [PDF]

Front Cell Dev Biol
You S, Sun Y, Li N, Xie H, Zeng X, Su X, Liu D, Shao C, Dai A.   +8 more
europepmc   +1 more source

Drought and salinity stress remodel Asian rice (Oryza sativa) leaf development through cell‐type‐specific regulatory programs

New Phytologist, EarlyView.
Osmotic stressors induce developmental and physiological changes in rice (Oryza sativa) seedlings, which are modulated by cell‐type‐specific gene expression and regulatory networks. We exposed plants to two levels of drought and salinity stress and measured the effects of these stressors on developing leaves by measuring physiological traits, ion ...
Sean M. Robertson, Obaid Maqsood, Chi Dang, Asher Pasha, Claudio Stasolla, Nicholas J. Provart, Olivia Wilkins   +6 more
wiley   +1 more source

Transcatheter Therapy in Secondary Mitral Regurgitation: Recent Clinical Evidence and Emerging Frontiers. [PDF]

Cureus
Torres Á, Jochava R, Quintanilla F, Córdova C, Krögh G, Besa S.   +5 more
europepmc   +1 more source

The combination of morphogenic regulators BABY BOOM and GRF‐GIF improves maize transformation efficiency and promotes leaf regeneration

New Phytologist, EarlyView.
Maize regeneration via somatic embryogenesis by ectopic expression of morphogenic factors TaGRF4‐TaGIF1 and ZmBBM. Summary Transformation is an indispensable tool for plant genetics and functional genomics. Although stable transformation in maize is no longer a major obstacle, there remains a need for accessible and efficient methods for academic ...
Zongliang Chen, Jiaqi Zhou, Mary Galli, Sessen Daniel Iohannes, Theresa Clark, Juan M. Debernardi, Jorge Dubcovsky, David Jackson, Andrea Gallavotti   +8 more
wiley   +1 more source

Clinical and radiographic outcomes of the SMR TT system - a novel convertible all-polyethylene glenoid with hybrid fixation in anatomic total shoulder arthroplasty: minimum 5-year follow-up. [PDF]

J Shoulder Elb Arthroplast
Dutta A, Chatindiara I, Buckley N, Gao R, Poon PC.   +4 more
europepmc   +1 more source

Heterodimeric SMR, EbrAB: Determination of Transmembrane Topology and Transformation of Each Component into Homodimeric SMR

Seibutsu Butsuri, 2007
KIKUKAWA, Takashi, NARA, Toshifumi
openaire   +2 more sources

A Century of Understanding and Harnessing Heterosis

Plant Breeding, EarlyView.
ABSTRACT Heterosis has shaped modern plant breeding since Darwin's 19th century observations that outcrossing restores vigour lost through selfing. While 100 years old, its mechanistic basis and deployability remain actively debated. Classical models of dominance, overdominance and epistasis provided the foundation for hybrid breeding and converted ...
Mohsen Mohammadi
wiley   +1 more source

Left ventricular reverse remodelling after mitral transcatheter edge-to-edge repair: results from the EXPANDed studies. [PDF]

ESC Heart Fail
Keßler M, Tang GHL, Deferm S, Estevez-Loureiro R, Rottbauer W, Asch FM, Zamorano JL, Aiyer J, Huang R, Rodriguez E, Kar S, Maisano F, von Bardeleben RS.   +12 more
europepmc   +1 more source