Results 121 to 130 of about 299,181 (381)

USP45 Represses Melanoma Development by Deubiquitinating and Stabilizing Tumor Suppressor MRGPRF

Advanced Science, EarlyView.
USP45 acts as a melanoma suppressor by stabilizing MRGPRF, which weakens the PI3K/AKT pathway, suppresses tumor growth, and reduces melanoma cell migration and invasion. Abstract Melanoma, a highly malignant skin cancer, has seen a rising incidence and death toll. MRGPRF is a novel melanoma suppressor that inhibits the PI3K/AKT pathway.
Wancong Zhang, Liyun Chen, Jing Zhao, Aiwei Ma, Wenqi Shi, Yiwen Zhang, Zixuan Tang, Jiarui Guo, Zaihua Xu, Jianda Zhou, Shijie Tang   +10 more
wiley   +1 more source

New species of stygobiotic Belgrandiella from north Bulgaria (Gastropoda: Hydrobiidae)

Biologica Nyssana, 2012
A new stygobiotic species of Belgrandiella from a cave in north Bulgaria was described. Nine shells were collected by the author on 09.03.2013 at the entrance of the Water cave (Vodnata) near village of Musina, north Bulgaria, N43 13 14.9 E25 25 39.6 ...
Georgiev, D.
doaj  

Shear stress induces endothelial-to-mesenchymal transition via the transcription factor Snail

Scientific Reports, 2017
Blood flow influences atherosclerosis by generating wall shear stress, which alters endothelial cell (EC) physiology. Low shear stress induces dedifferentiation of EC through a process termed endothelial-to-mesenchymal transition (EndMT).
Marwa Mahmoud, J. Serbanovic-Canic, Shuang Feng, Celine Souilhol, Rouyu Xing, S. Hsiao, A. Mammoto, J. Chen, M. Ariaans, S. Francis, K. van der Heiden, V. Ridger, P. Evans   +12 more
semanticscholar   +1 more source

Effects of water temperature on summer periphyton biomass in shallow lakes: a pan-European mesocosm experiment [PDF]

, 2015
Periphyton communities play an important role in shallow lakes and are controlled by direct forces such as temperature, light, nutrients, and invertebrate grazing, but also indirectly by planktivorous fish predation.
Adrian, Rita, Beklioğlu, Meryem, Filiz, Nur, Hejzlar, Josef, Hilt, Sabine, Mahdy, Aldoushy, Papastergiadou, Eva, Scharfenberger, Ulrike, Özkundakci, Deniz, Šorf, Michal [u.v.m.]   +9 more
core   +1 more source

NamiRNA‐Enhancer Network: The Changing Era Challenge and Chance of miRNA

Advanced Science, EarlyView.
MiRNAs (miRNAs) regulate diverse biological processes across species. Unlike canonical miRNA‐mediated gene repression, Nuclear Activating miRNAs (NamiRNAs) can efficiently upregulate gene expression by targeting enhancers. This review systematically summarizes recent advances in NamiRNA research, elucidates the theory of NamiRNA‐Enhancer‐mediated Gene ...
Lu Chen, Ying Liang, Hongyan Wei, Mengxing Liu, Jin Wu, Wei Li, Wenxuan Li, Yuxiao Jin, Yinshan Li, Wei Zhao, Min Xiao, Kaicheng Zhou, Shuai Yang, Wenqiang Yu   +13 more
wiley   +1 more source

Effects of Ingestion of Lithic Particles on Growth of the Apple Snail Pomacea canaliculata (Caenogastropoda, Ampullariidae) [PDF]

, 2016
Lithic particles are a common feature in the digestive tract of freshwater snails. Their role in the digestive processes has been demonstrated in some microphytophagous and detritivorous species, as they enhance growth, assimilation and reproduction.
Manara, Enzo, Martín, Pablo Rafael, Saveanu, Lucía   +2 more
core   +1 more source

An LCN2‐Dependent Positive‐Feedback Loop Between Gastric Cancer Cells and Tumor‐Associated‐Macrophages Mediates Lymphangiogenesis and Lymphatic Metastasis

Advanced Science, EarlyView.
In this study, the expression and function of LCN2 in GC is aimed to investigate and elucidate the mechanisms by which the LCN2‐dependent positive‐feedback loop between GC cells and TAMs drives lymphangiogenesis and lymphatic metastasis. These findings suggest that LCN2 may serve as a potential prognostic biomarker and therapeutic target in GC ...
Zhixin Huang, Ying Li, Yan Qian, Linying Ye, Tianhao Zhang, Yang Cheng, Jialin Wu, Peng Duan, Tiantian Zhang, Zihan Yu, Zeyu Zhao, Risheng Zhao, Zhi Liang, Ertao Zhai, Shirong Cai, Jianhui Chen   +15 more
wiley   +1 more source

Hologenomics Reveals Specialized Dietary Adaptations in the Mengla Snail‐Eating Snake

Advanced Science, EarlyView.
Dietary adaptation studies from a holobiome perspective are scarce beyond mammals. This research reveals how genomic and microbial interactions drive dietary specialization in the Mengla snail‐eating snake, with evidence of gut symbiont convergence between reptiles and mammals.
Chaochao Yan, Xin‐Ning Li, Zhong‐Liang Peng, Wei Wu, Zeng Wang, Zhao‐Ran Zhu, Jia‐Chang Liu, Yao Wang, Jin‐Long Ren, Zhi‐Yi Zhang, Jia‐Tang Li   +10 more
wiley   +1 more source

HelixComplex snail mucus exhibits pro-survival, proliferative and pro-migration effects on mammalian fibroblasts

Scientific Reports, 2018
Snail mucus is a mixture of active substances commonly thought to have healthy properties for the treatment of skin disorders. Although snail mucus is an ingredient of several cosmetic and para-pharmaceutic products, a comprehensive characterization of ...
C. Trapella, R. Rizzo, Stefania Gallo, A. Alogna, D. Bortolotti, F. Casciano, G. Zauli, P. Secchiero, R. Voltan   +8 more
semanticscholar   +1 more source

Modelling environmentally-mediated infectious diseases of humans: transmission dynamics of schistosomiasis in China. [PDF]

, 2010
Macroparasites of humans are sensitive to a variety of environmental variables, including temperature, rainfall and hydrology, yet current comprehension of these relationships is limited.
Remais, Justin
core   +1 more source