Long non‐coding RNAs (lncRNAs), a broad class of non‐protein‐coding RNAs, are characterized as new regulators of gene expression at the epigenetic, transcriptional, and post‐transcriptional level. Thus, lncRNAs are involved in the regulation of physiological processes and the development of human diseases and cancer by modulating proinflammatory ...
Charlie Leboff +3 more
wiley +1 more source
Lessons from history: mass mobilization and public health campaigns in China's anti-schistosomiasis efforts (1950s-1980s). [PDF]
Guo QL, Chen HB.
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RUNX1‐Driven CPXM1 Transcription Promotes Malignant Phenotypes and EMT in Gastric Cancer Cells
RUNX1 transcriptionally activates CPXM1, promotes EMT, and enhances the proliferation, invasion, and metastasis of gastric cancer cells. ABSTRACT Gastric cancer (GC) remains a leading cause of cancer‐related mortality worldwide, with current treatment strategies largely limited to surgery, chemotherapy, and targeted therapy.
Ping Jia +8 more
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A county-level indicator framework for assessing schistosomiasis transmission risk in post-transmission-interruption China. [PDF]
Xu A +8 more
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Pleiotropic Roles of FBXO11 in Tumorigenesis: Implications for Targeted Therapy
This complex comprises of scaffold CUL1, SKP1, RBX1 and FBXO11 receptor. The substrate is phosphorylated by specific kinase enzyme and recognized by the substrate recognition domain. FBXO11 targets numerous substrates for ubiquitination and degradation, FBXO11 substrates mainly include Snail, ZEB1, p53, BCL6, CDT2, CIITA, Cdc25a, hnRNPA2B1, SAMD1 and ...
Yuqi Zhang +6 more
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Regulatory mechanisms for Snail protein stability: ubiquitin-proteasome system and chaperone-mediated autophagy. [PDF]
Kim M, Hong KS, Kim T, Ryu KJ, Yoo J.
europepmc +1 more source
Abstract Adaptive management of threatened species relies on having ex ante estimates of species’ responses to different interventions. Structured expert elicitation is often used to generate these estimates, but comparisons of these expert‐predicted outcomes with observed results are rare.
Helen J. Mayfield +18 more
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<i>ZNF528</i> as a novel driver of metastasis in lung cancer: insights from single-cell transcriptomics. [PDF]
Li H +8 more
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Abstract Pigments (extracts) from Stramonita (Thais) haemastoma and Bolinus (Murex) brandaris molluscs, which were collected along the coastline of Tunisia and processed under sunlight, are analysed using High Performance Liquid Chromatography (HPLC) coupled to a Diode Array Detector (DAD).
Athina Vasileiadou +3 more
wiley +1 more source
Hesperidin Inhibits Proliferation and Metastasis of Human Breast Cancer Cells by Suppressing MMP-2/9 Activity and Reversing Epithelial-Mesenchymal Transition. [PDF]
Hu H, Zhang C, Liu Z.
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