Results 151 to 160 of about 215,951 (299)

Inhibition of PHF1 promotes ferroptosis via IRES‐dependent Snail translation regulation in pancreatic ductal adenocarcinoma

VIEW, EarlyView.
PHF1 is a known epigenetic regulator involved in transcriptional silencing in cancer. In this study, we identified PHF1 as an oncogene that promotes PDAC progression and demonstrated that its inhibition induces ferroptosis. Mechanistically, PHF1 physically interacts with the FBL/NOP56/NOP58 snoRNP complex to enhance the IRES‐dependent translation of ...
Yujiao Xie, Shan Jin, Yao Zhan, Tiantian Du, Yaqi Dong, Peilong Li, Xiaoshi Zhang, Qiuchen Qi, Jie Gao, Chuanxin Wang   +9 more
wiley   +1 more source

Regulatory mechanisms for Snail protein stability: ubiquitin-proteasome system and chaperone-mediated autophagy. [PDF]

Exp Mol Med
Kim M, Hong KS, Kim T, Ryu KJ, Yoo J.
europepmc   +1 more source

Delisting the Northern Rocky Mountain gray wolf from the US Endangered Species Act: an assessment of political discourse over 20 years

Wildlife Biology, EarlyView.
Feared, revered, and politicized, wolves have long captured human imagination, and ignited fierce conservation conflicts. In the United States, the Endangered Species Act protects species at risk of extinction from human impacts. This far‐reaching legislation, which impacts development and state‐level wildlife management, has been fraught with legal ...
Iree Wheeler, Paisley Blair, Noah Creany, Hannah Manire, Daniel Morris, Sofia Mollett, Steelle S. Scearce, Temple Stoellinger, Janna R. Willoughby, Kelly H. Dunning   +9 more
wiley   +1 more source

Abundance and Seasonal Variations of Snail Intermediate Hosts of Schistosomiasis in the Federal Capital Territory, Abuja, Nigeria. [PDF]

Int J Environ Res Public Health
Anagbogu IN, Jacob SM, Malann YD, Dankishiya AS, Abubakar A, Agbana T, Diehl JC, Madara AA.   +7 more
europepmc   +1 more source

Local Ecological Knowledge Reveals the Distribution of Cryptic Nocturnal Wildlife

Wildlife Letters, EarlyView.
Many nocturnal animals are difficult to study because they are rarely seen, including nocturnal primates, galagos and pottos, in West Africa. Working with over 600 people in 52 villages in southern Guinea‐Bissau, we found that communities frequently recognized galagos by their red eyeshine and distinctive calls, while pottos were not known.
Chloe Chesney, Iaia Tawél Camará, Mamadu Cassamá, Amélia Frazão‐Moreira, Tânia Minhós, Kimberley J. Hockings, Elena Bersacola   +6 more
wiley   +1 more source

Transcriptome profiling of intra-snail stages of the liver fluke Fasciola hepatica reveals key mediators underlying parasite development and interaction with the host. [PDF]

BMC Genomics
Langleib M, Fontenla S, Domínguez F, Sankaranarayanan G, Wlodek S, Berriman M, Rinaldi G, Iriarte A, Tort JF.   +8 more
europepmc   +1 more source

Can manipulative parasites modify host‐mediated trophic effects? Experimental evidence from Schistocephalus solidus and three‐spined sticklebacks

Functional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Parasites can alter host traits, thereby reshaping host interactions and modifying density‐ and trait‐mediated effects in trophic cascades. But despite increasing research in parasite ecology, the cascading effects of parasitism from individual hosts to population and ...
Maja Drakula, Lena Gerigk, Ella S. Rothe, Jacob‐Josef Brüning, Mats Reckert, Alexander Brinker, Beatriz Elias Ranelli, Joachim Kurtz, Jaime M. Anaya‐Rojas   +8 more
wiley   +1 more source

Limited impact of schistosome infection on Biomphalaria glabrata snail microbiomes. [PDF]

Parasit Vectors
Nordmeyer SC, Anderson TJC, Le Clec'h W, Chevalier FD.   +3 more
europepmc   +1 more source

Invasive goldfish trigger a regime shift in experimental lake ecosystems of varying trophic state

Journal of Animal Ecology, EarlyView.
The pet trade distributes exotic animals around the globe that enrich human lives. However, some pets become pests when released into the wild. This study provides experimental evidence that goldfish will negatively affect native freshwater organisms and ecosystems.
William D. Hintz, Hannah Barrett, Rick A. Relyea   +2 more
wiley   +1 more source

DICER1 dysregulation triggers reprogramming of a specific miRNA subset, promotes mesenchymal cell fates and slows TNBC tumorigenic phenotypes. [PDF]

Noncoding RNA Res
Koshre G, Khan M, Rajasekaran S, Manning AL, Walker JA, Miles WO.   +5 more
europepmc   +1 more source