Results 151 to 160 of about 79,869 (259)

Long non‐coding RNAs at the crossroads of inflammation, cancer and angiogenesis: Molecular mechanisms and their potential as therapeutic targets

open access: yesBritish Journal of Pharmacology, EarlyView.
Long non‐coding RNAs (lncRNAs), a broad class of non‐protein‐coding RNAs, are characterized as new regulators of gene expression at the epigenetic, transcriptional, and post‐transcriptional level. Thus, lncRNAs are involved in the regulation of physiological processes and the development of human diseases and cancer by modulating proinflammatory ...
Charlie Leboff   +3 more
wiley   +1 more source

RUNX1‐Driven CPXM1 Transcription Promotes Malignant Phenotypes and EMT in Gastric Cancer Cells

open access: yesCancer Science, EarlyView.
RUNX1 transcriptionally activates CPXM1, promotes EMT, and enhances the proliferation, invasion, and metastasis of gastric cancer cells. ABSTRACT Gastric cancer (GC) remains a leading cause of cancer‐related mortality worldwide, with current treatment strategies largely limited to surgery, chemotherapy, and targeted therapy.
Ping Jia   +8 more
wiley   +1 more source

Pleiotropic Roles of FBXO11 in Tumorigenesis: Implications for Targeted Therapy

open access: yesCancer Science, EarlyView.
This complex comprises of scaffold CUL1, SKP1, RBX1 and FBXO11 receptor. The substrate is phosphorylated by specific kinase enzyme and recognized by the substrate recognition domain. FBXO11 targets numerous substrates for ubiquitination and degradation, FBXO11 substrates mainly include Snail, ZEB1, p53, BCL6, CDT2, CIITA, Cdc25a, hnRNPA2B1, SAMD1 and ...
Yuqi Zhang   +6 more
wiley   +1 more source

Evaluating a structured expert elicitation approach for adaptive conservation management based on lessons from five years in practice

open access: yesConservation Biology, EarlyView.
Abstract Adaptive management of threatened species relies on having ex ante estimates of species’ responses to different interventions. Structured expert elicitation is often used to generate these estimates, but comparisons of these expert‐predicted outcomes with observed results are rare.
Helen J. Mayfield   +18 more
wiley   +1 more source

<i>ZNF528</i> as a novel driver of metastasis in lung cancer: insights from single-cell transcriptomics. [PDF]

open access: yesTransl Lung Cancer Res
Li H   +8 more
europepmc   +1 more source

Chemical compositions of Stramonita haemastoma and Bolinus brandaris: New data relevant to cultural heritage studies

open access: yesColoration Technology, EarlyView.
Abstract Pigments (extracts) from Stramonita (Thais) haemastoma and Bolinus (Murex) brandaris molluscs, which were collected along the coastline of Tunisia and processed under sunlight, are analysed using High Performance Liquid Chromatography (HPLC) coupled to a Diode Array Detector (DAD).
Athina Vasileiadou   +3 more
wiley   +1 more source

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